1q6y

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[[Image:1q6y.gif|left|200px]]<br /><applet load="1q6y" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1q6y.gif|left|200px]]
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caption="1q6y, resolution 1.99&Aring;" />
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'''Hypothetical protein YfdW from E. coli bound to Coenzyme A'''<br />
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{{Structure
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|PDB= 1q6y |SIZE=350|CAPTION= <scene name='initialview01'>1q6y</scene>, resolution 1.99&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=COA:COENZYME+A'>COA</scene> and <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>
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|ACTIVITY=
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|GENE= YFDW ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
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}}
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'''Hypothetical protein YfdW from E. coli bound to Coenzyme A'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1Q6Y is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=COA:'>COA</scene> and <scene name='pdbligand=MPD:'>MPD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q6Y OCA].
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1Q6Y is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q6Y OCA].
==Reference==
==Reference==
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Structure of Escherichia coli YfdW, a type III CoA transferase., Gogos A, Gorman J, Shapiro L, Acta Crystallogr D Biol Crystallogr. 2004 Mar;60(Pt 3):507-11. Epub 2004, Feb 25. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=14993676 14993676]
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Structure of Escherichia coli YfdW, a type III CoA transferase., Gogos A, Gorman J, Shapiro L, Acta Crystallogr D Biol Crystallogr. 2004 Mar;60(Pt 3):507-11. Epub 2004, Feb 25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14993676 14993676]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: COA]]
[[Category: COA]]
[[Category: MPD]]
[[Category: MPD]]
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[[Category: coenzyme a]]
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[[Category: coenzyme some]]
[[Category: intertwined dimer]]
[[Category: intertwined dimer]]
[[Category: new york structural genomix research consortium]]
[[Category: new york structural genomix research consortium]]
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[[Category: protein structure initiative]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: psi]]
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[[Category: structural genomics]]
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[[Category: structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:36:32 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:33:48 2008''

Revision as of 11:33, 20 March 2008


PDB ID 1q6y

Drag the structure with the mouse to rotate
, resolution 1.99Å
Ligands: and
Gene: YFDW (Escherichia coli)
Coordinates: save as pdb, mmCIF, xml



Hypothetical protein YfdW from E. coli bound to Coenzyme A


Overview

Crystal structures are reported for free and coenzyme A (CoA) bound forms of the YfdW protein from Escherichia coli, a representative type III CoA transferase. The structures reveal a two-domain protomer with interdomain connections forming a ring-like structure with a large central hole. Two protomers associate to form a highly intertwined dimer in which the hole of each ring is filled by the partner molecule. Each protomer binds a single CoA molecule and these CoA-binding sites are distant from one another in the dimer.

About this Structure

1Q6Y is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Structure of Escherichia coli YfdW, a type III CoA transferase., Gogos A, Gorman J, Shapiro L, Acta Crystallogr D Biol Crystallogr. 2004 Mar;60(Pt 3):507-11. Epub 2004, Feb 25. PMID:14993676

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