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3ico

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{{STRUCTURE_3ico| PDB=3ico | SCENE= }}
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==Crystal structure of 6-phosphogluconolactonase from Mycobacterium tuberculosis==
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===Crystal structure of 6-phosphogluconolactonase from Mycobacterium tuberculosis===
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<StructureSection load='3ico' size='340' side='right' caption='[[3ico]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[3ico]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ICO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ICO FirstGlance]. <br>
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[[http://www.uniprot.org/uniprot/6PGL_MYCTU 6PGL_MYCTU]] Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pgl, devB, Rv1445c, MT1492, MTCY493.09 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr>
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==About this Structure==
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/6-phosphogluconolactonase 6-phosphogluconolactonase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.31 3.1.1.31] </span></td></tr>
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[[3ico]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ICO OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ico FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ico OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ico RCSB], [http://www.ebi.ac.uk/pdbsum/3ico PDBsum]</span></td></tr>
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</table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ic/3ico_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: 6-phosphogluconolactonase]]
[[Category: 6-phosphogluconolactonase]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: SSGCID, Seattle Structural Genomics Center for Infectious Disease.]]
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[[Category: Structural genomic]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Infectious disease]]
[[Category: Infectious disease]]
[[Category: Niaid]]
[[Category: Niaid]]
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[[Category: Seattle structural genomics center for infectious disease]]
 
[[Category: Ssgcid]]
[[Category: Ssgcid]]
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[[Category: Structural genomic]]
 

Revision as of 15:09, 18 December 2014

Crystal structure of 6-phosphogluconolactonase from Mycobacterium tuberculosis

3ico, resolution 2.15Å

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