3ma6
From Proteopedia
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| - | + | ==Crystal structure of kinase domain of TgCDPK1 in presence of 3BrB-PP1== | |
| - | + | <StructureSection load='3ma6' size='340' side='right' caption='[[3ma6]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[3ma6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Toxoplasma_gondii Toxoplasma gondii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MA6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MA6 FirstGlance]. <br> |
| - | [[3ma6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Toxoplasma_gondii Toxoplasma gondii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MA6 OCA]. | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DXR:3-(3-BROMOBENZYL)-1-TERT-BUTYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE'>DXR</scene></td></tr> |
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CDPK1, TGME49_101440 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5811 Toxoplasma gondii])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ma6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ma6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ma6 RCSB], [http://www.ebi.ac.uk/pdbsum/3ma6 PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ma/3ma6_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Toxoplasma gondii]] | [[Category: Toxoplasma gondii]] | ||
| - | [[Category: Amani, M | + | [[Category: Amani, M]] |
| - | [[Category: Arrowsmith, C H | + | [[Category: Arrowsmith, C H]] |
| - | [[Category: Artz, J D | + | [[Category: Artz, J D]] |
| - | [[Category: Bochkarev, A | + | [[Category: Bochkarev, A]] |
| - | [[Category: Bountra, C | + | [[Category: Bountra, C]] |
| - | [[Category: Edwards, A M | + | [[Category: Edwards, A M]] |
| - | [[Category: Hassani, A A | + | [[Category: Hassani, A A]] |
| - | [[Category: Hui, R | + | [[Category: Hui, R]] |
| - | [[Category: Lin, Y H | + | [[Category: Lin, Y H]] |
| - | [[Category: Lourido, S | + | [[Category: Lourido, S]] |
| - | [[Category: Qiu, W | + | [[Category: Qiu, W]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Senisterra, G | + | [[Category: Senisterra, G]] |
| - | [[Category: Shokat, K | + | [[Category: Shokat, K]] |
| - | [[Category: Sibley, L D | + | [[Category: Sibley, L D]] |
| - | [[Category: Vedadi, M | + | [[Category: Vedadi, M]] |
| - | [[Category: Weigelt, J | + | [[Category: Weigelt, J]] |
| - | [[Category: Wernimont, A K | + | [[Category: Wernimont, A K]] |
| - | [[Category: Zhang, C | + | [[Category: Zhang, C]] |
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Cdpk]] | [[Category: Cdpk]] | ||
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[[Category: Serine/threonine-protein kinase]] | [[Category: Serine/threonine-protein kinase]] | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
| - | [[Category: Structural genomic]] | ||
| - | [[Category: Structural genomics consortium]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 15:44, 18 December 2014
Crystal structure of kinase domain of TgCDPK1 in presence of 3BrB-PP1
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Categories: Toxoplasma gondii | Amani, M | Arrowsmith, C H | Artz, J D | Bochkarev, A | Bountra, C | Edwards, A M | Hassani, A A | Hui, R | Lin, Y H | Lourido, S | Qiu, W | Structural genomic | Senisterra, G | Shokat, K | Sibley, L D | Vedadi, M | Weigelt, J | Wernimont, A K | Zhang, C | Atp-binding | Cdpk | Kinase | Nucleotide-binding | Parasitology | Serine/threonine-protein kinase | Sgc | Transferase
