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3mii

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{{STRUCTURE_3mii| PDB=3mii | SCENE= }}
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==Crystal structure of Y0R391Cp/HSP33 from Saccharomyces cerevisiae==
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===Crystal structure of Y0R391Cp/HSP33 from Saccharomyces cerevisiae===
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<StructureSection load='3mii' size='340' side='right' caption='[[3mii]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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{{ABSTRACT_PUBMED_21139195}}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3mii]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MII OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MII FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3kkl|3kkl]], [[1qvv|1qvv]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">YOR091C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mii FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mii OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mii RCSB], [http://www.ebi.ac.uk/pdbsum/3mii PDBsum]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Saccharomyces cerevisiae Hsp33/YOR391Cp is a member of the ThiI/DJ-1/PfpI superfamily. Hsp33 was overexpressed in Escherichia coli and its crystal structure was determined at 2.40 A resolution. Structural comparison revealed that Hsp33 adopts an alpha/beta-hydrolase fold and possesses the putative Cys-His-Glu catalytic triad common to the Hsp31 family, suggesting that Hsp33 and Hsp31 share similar aminopeptidase activity, while structural deviations in helices alpha2-alpha3 of the core domain might be responsible for the access of different peptide substrates.
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==Function==
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Structure of Hsp33/YOR391Cp from the yeast Saccharomyces cerevisiae.,Guo PC, Zhou YY, Ma XX, Li WF Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Dec 1;66(Pt, 12):1557-61. Epub 2010 Nov 16. PMID:21139195<ref>PMID:21139195</ref>
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[[http://www.uniprot.org/uniprot/HSP33_YEAST HSP33_YEAST]] Probable protease. May act as a chaperone (By similarity).
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==About this Structure==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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[[3mii]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MII OCA].
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</div>
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:021139195</ref><references group="xtra"/><references/>
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__TOC__
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</StructureSection>
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Guo, P C.]]
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[[Category: Guo, P C]]
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[[Category: Li, W F.]]
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[[Category: Li, W F]]
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[[Category: Zhou, C Z.]]
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[[Category: Zhou, C Z]]
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[[Category: Zhou, Y Y.]]
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[[Category: Zhou, Y Y]]
[[Category: Heat shock protein]]
[[Category: Heat shock protein]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]

Revision as of 15:44, 18 December 2014

Crystal structure of Y0R391Cp/HSP33 from Saccharomyces cerevisiae

3mii, resolution 2.40Å

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