1qd9
From Proteopedia
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| - | [[Image:1qd9.gif|left|200px]] | + | [[Image:1qd9.gif|left|200px]] |
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| - | '''Bacillus subtilis YABJ''' | + | {{Structure |
| + | |PDB= 1qd9 |SIZE=350|CAPTION= <scene name='initialview01'>1qd9</scene>, resolution 1.70Å | ||
| + | |SITE= | ||
| + | |LIGAND= <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=EMC:ETHYL+MERCURY+ION'>EMC</scene> and <scene name='pdbligand=ACY:ACETIC ACID'>ACY</scene> | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''Bacillus subtilis YABJ''' | ||
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==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1QD9 is a [ | + | 1QD9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QD9 OCA]. |
==Reference== | ==Reference== | ||
| - | Crystal structure of Bacillus subtilis YabJ, a purine regulatory protein and member of the highly conserved YjgF family., Sinha S, Rappu P, Lange SC, Mantsala P, Zalkin H, Smith JL, Proc Natl Acad Sci U S A. 1999 Nov 9;96(23):13074-9. PMID:[http:// | + | Crystal structure of Bacillus subtilis YabJ, a purine regulatory protein and member of the highly conserved YjgF family., Sinha S, Rappu P, Lange SC, Mantsala P, Zalkin H, Smith JL, Proc Natl Acad Sci U S A. 1999 Nov 9;96(23):13074-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10557275 10557275] |
[[Category: Bacillus subtilis]] | [[Category: Bacillus subtilis]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: yjgf/yer057c family]] | [[Category: yjgf/yer057c family]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:36:09 2008'' |
Revision as of 11:36, 20 March 2008
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| , resolution 1.70Å | |||||||
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| Ligands: | , and | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Bacillus subtilis YABJ
Overview
The yabJ gene in Bacillus subtilis is required for adenine-mediated repression of purine biosynthetic genes in vivo and codes for an acid-soluble, 14-kDa protein. The molecular mechanism of YabJ is unknown. YabJ is a member of a large, widely distributed family of proteins of unknown biochemical function. The 1.7-A crystal structure of YabJ reveals a trimeric organization with extensive buried hydrophobic surface and an internal water-filled cavity. The most important finding in the structure is a deep, narrow cleft between subunits lined with nine side chains that are invariant among the 25 most similar homologs. This conserved site is proposed to be a binding or catalytic site for a ligand or substrate that is common to YabJ and other members of the YER057c/YjgF/UK114 family of proteins.
About this Structure
1QD9 is a Single protein structure of sequence from Bacillus subtilis. Full crystallographic information is available from OCA.
Reference
Crystal structure of Bacillus subtilis YabJ, a purine regulatory protein and member of the highly conserved YjgF family., Sinha S, Rappu P, Lange SC, Mantsala P, Zalkin H, Smith JL, Proc Natl Acad Sci U S A. 1999 Nov 9;96(23):13074-9. PMID:10557275
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