1qdn

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[[Image:1qdn.jpg|left|200px]]<br /><applet load="1qdn" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1qdn.jpg|left|200px]]
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caption="1qdn, resolution 2.30&Aring;" />
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'''AMINO TERMINAL DOMAIN OF THE N-ETHYLMALEIMIDE SENSITIVE FUSION PROTEIN (NSF)'''<br />
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{{Structure
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|PDB= 1qdn |SIZE=350|CAPTION= <scene name='initialview01'>1qdn</scene>, resolution 2.30&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>
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|ACTIVITY=
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|GENE=
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}}
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'''AMINO TERMINAL DOMAIN OF THE N-ETHYLMALEIMIDE SENSITIVE FUSION PROTEIN (NSF)'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1QDN is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Cricetulus_griseus Cricetulus griseus] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=BME:'>BME</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QDN OCA].
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1QDN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Cricetulus_griseus Cricetulus griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QDN OCA].
==Reference==
==Reference==
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Crystal structure of the amino-terminal domain of N-ethylmaleimide-sensitive fusion protein., May AP, Misura KM, Whiteheart SW, Weis WI, Nat Cell Biol. 1999 Jul;1(3):175-82. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10559905 10559905]
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Crystal structure of the amino-terminal domain of N-ethylmaleimide-sensitive fusion protein., May AP, Misura KM, Whiteheart SW, Weis WI, Nat Cell Biol. 1999 Jul;1(3):175-82. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10559905 10559905]
[[Category: Cricetulus griseus]]
[[Category: Cricetulus griseus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: vesicular-fusion protein]]
[[Category: vesicular-fusion protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:38:39 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:36:16 2008''

Revision as of 11:36, 20 March 2008

Image:1qdn.jpg


PDB ID 1qdn

Drag the structure with the mouse to rotate
, resolution 2.30Å
Ligands: and
Coordinates: save as pdb, mmCIF, xml



AMINO TERMINAL DOMAIN OF THE N-ETHYLMALEIMIDE SENSITIVE FUSION PROTEIN (NSF)


Overview

The cytosolic ATPase N-ethylmaleimide-sensitive fusion protein (NSF) disassembles complexes of membrane-bound proteins known as SNAREs, an activity essential for vesicular trafficking. The amino-terminal domain of NSF (NSF-N) is required for the interaction of NSF with the SNARE complex through the adaptor protein alpha-SNAP. The crystal structure of NSF-N reveals two subdomains linked by a single stretch of polypeptide. A polar interface between the two subdomains indicates that they can move with respect to one another during the catalytic cycle of NSF. Structure-based sequence alignments indicate that in addition to NSF orthologues, the p97 family of ATPases contain an amino-terminal domain of similar structure.

About this Structure

1QDN is a Single protein structure of sequence from Cricetulus griseus. Full crystallographic information is available from OCA.

Reference

Crystal structure of the amino-terminal domain of N-ethylmaleimide-sensitive fusion protein., May AP, Misura KM, Whiteheart SW, Weis WI, Nat Cell Biol. 1999 Jul;1(3):175-82. PMID:10559905

Page seeded by OCA on Thu Mar 20 13:36:16 2008

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