This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3km8

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "3km8" [edit=sysop:move=sysop])
Line 1: Line 1:
-
{{STRUCTURE_3km8| PDB=3km8 | SCENE= }}
+
==Crystal structuore of adenosine deaminase from mus musculus complexed with 9-deazainosine==
-
===Crystal structuore of adenosine deaminase from mus musculus complexed with 9-deazainosine===
+
<StructureSection load='3km8' size='340' side='right' caption='[[3km8]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[3km8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KM8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3KM8 FirstGlance]. <br>
 +
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9DI:9-DEAZAINOSINE'>9DI</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
 +
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1add|1add]]</td></tr>
 +
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Ada ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
 +
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosine_deaminase Adenosine deaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.4 3.5.4.4] </span></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3km8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3km8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3km8 RCSB], [http://www.ebi.ac.uk/pdbsum/3km8 PDBsum]</span></td></tr>
 +
</table>
-
==Function==
+
==See Also==
-
[[http://www.uniprot.org/uniprot/ADA_MOUSE ADA_MOUSE]] Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion (By similarity).
+
*[[Adenosine deaminase|Adenosine deaminase]]
-
 
+
__TOC__
-
==About this Structure==
+
</StructureSection>
-
[[3km8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KM8 OCA].
+
[[Category: Adenosine deaminase]]
[[Category: Adenosine deaminase]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
-
[[Category: Fan, X.]]
+
[[Category: Fan, X]]
-
[[Category: Gao, Y.]]
+
[[Category: Gao, Y]]
[[Category: Cyclicamidine]]
[[Category: Cyclicamidine]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Metal-binding]]
[[Category: Metal-binding]]
[[Category: Nucleotide metabolism]]
[[Category: Nucleotide metabolism]]

Revision as of 16:02, 18 December 2014

Crystal structuore of adenosine deaminase from mus musculus complexed with 9-deazainosine

3km8, resolution 2.00Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools