3n2l

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{{STRUCTURE_3n2l| PDB=3n2l | SCENE= }}
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==2.1 Angstrom resolution crystal structure of an Orotate Phosphoribosyltransferase (pyrE) from Vibrio cholerae O1 biovar eltor str. N16961==
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===2.1 Angstrom resolution crystal structure of an Orotate Phosphoribosyltransferase (pyrE) from Vibrio cholerae O1 biovar eltor str. N16961===
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<StructureSection load='3n2l' size='340' side='right' caption='[[3n2l]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[3n2l]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N2L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3N2L FirstGlance]. <br>
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[[http://www.uniprot.org/uniprot/PYRE_VIBCH PYRE_VIBCH]] Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity).
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pyrE, VC_0211 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=666 Vibrio cholerae])</td></tr>
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==About this Structure==
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotate_phosphoribosyltransferase Orotate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.10 2.4.2.10] </span></td></tr>
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[[3n2l]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N2L OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3n2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n2l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3n2l RCSB], [http://www.ebi.ac.uk/pdbsum/3n2l PDBsum]</span></td></tr>
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</table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n2/3n2l_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[Phosphoribosyltransferase|Phosphoribosyltransferase]]
*[[Phosphoribosyltransferase|Phosphoribosyltransferase]]
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__TOC__
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</StructureSection>
[[Category: Orotate phosphoribosyltransferase]]
[[Category: Orotate phosphoribosyltransferase]]
[[Category: Vibrio cholerae]]
[[Category: Vibrio cholerae]]
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[[Category: Anderson, W F.]]
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[[Category: Anderson, W F]]
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[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
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[[Category: Structural genomic]]
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[[Category: Dubrovska, I.]]
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[[Category: Dubrovska, I]]
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[[Category: Halavaty, A S.]]
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[[Category: Halavaty, A S]]
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[[Category: Kwon, K.]]
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[[Category: Kwon, K]]
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[[Category: Minasov, G.]]
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[[Category: Minasov, G]]
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[[Category: Shuvalova, L.]]
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[[Category: Shuvalova, L]]
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[[Category: Winsor, J.]]
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[[Category: Winsor, J]]
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[[Category: Center for structural genomics of infectious disease]]
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[[Category: Csgid]]
[[Category: Csgid]]
[[Category: Glycosyltransferase]]
[[Category: Glycosyltransferase]]
[[Category: Infectious disease]]
[[Category: Infectious disease]]
[[Category: Magnesium]]
[[Category: Magnesium]]
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[[Category: Orotate phosphoribosyltransferase]]
 
[[Category: Pyrimidine biosynthesis]]
[[Category: Pyrimidine biosynthesis]]
[[Category: Pyrimidine ribonucleotide biosynthesis]]
[[Category: Pyrimidine ribonucleotide biosynthesis]]
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 16:06, 18 December 2014

2.1 Angstrom resolution crystal structure of an Orotate Phosphoribosyltransferase (pyrE) from Vibrio cholerae O1 biovar eltor str. N16961

3n2l, resolution 2.10Å

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