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1qfx

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[[Image:1qfx.jpg|left|200px]]<br /><applet load="1qfx" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1qfx.jpg|left|200px]]
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caption="1qfx, resolution 2.4&Aring;" />
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'''PH 2.5 ACID PHOSPHATASE FROM ASPERGILLUS NIGER'''<br />
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{{Structure
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|PDB= 1qfx |SIZE=350|CAPTION= <scene name='initialview01'>1qfx</scene>, resolution 2.4&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
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|ACTIVITY= [http://en.wikipedia.org/wiki/3-phytase 3-phytase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.8 3.1.3.8]
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|GENE=
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}}
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'''PH 2.5 ACID PHOSPHATASE FROM ASPERGILLUS NIGER'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1QFX is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Aspergillus_niger Aspergillus niger] with <scene name='pdbligand=NAG:'>NAG</scene>, <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/3-phytase 3-phytase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.8 3.1.3.8] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QFX OCA].
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1QFX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Aspergillus_niger Aspergillus niger]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QFX OCA].
==Reference==
==Reference==
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Crystal structure of Aspergillus niger pH 2.5 acid phosphatase at 2. 4 A resolution., Kostrewa D, Wyss M, D'Arcy A, van Loon AP, J Mol Biol. 1999 May 21;288(5):965-74. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=10329192 10329192]
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Crystal structure of Aspergillus niger pH 2.5 acid phosphatase at 2. 4 A resolution., Kostrewa D, Wyss M, D'Arcy A, van Loon AP, J Mol Biol. 1999 May 21;288(5):965-74. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10329192 10329192]
[[Category: 3-phytase]]
[[Category: 3-phytase]]
[[Category: Aspergillus niger]]
[[Category: Aspergillus niger]]
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[[Category: phosphomonoesterase]]
[[Category: phosphomonoesterase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:39:06 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:36:54 2008''

Revision as of 11:36, 20 March 2008

Image:1qfx.jpg


PDB ID 1qfx

Drag the structure with the mouse to rotate
, resolution 2.4Å
Ligands: , and
Activity: 3-phytase, with EC number 3.1.3.8
Coordinates: save as pdb, mmCIF, xml



PH 2.5 ACID PHOSPHATASE FROM ASPERGILLUS NIGER


Overview

The crystal structure of Aspergillus niger pH 2.5 acid phosphatase (EC 3.1.3.2) has been determined at 2.4 A resolution. In the crystal, two dimers form a tetramer in which the active sites are easily accessible to substrates. The main contacts in the dimer come from the N termini, each lying on the surface of the neighbouring molecule. The monomer consists of two domains, with the active site located at their interface. The active site has a highly conserved catalytic center and a charge distribution, which explains the highly acidic pH optimum and the broad substrate specificity of the enzyme.

About this Structure

1QFX is a Single protein structure of sequence from Aspergillus niger. Full crystallographic information is available from OCA.

Reference

Crystal structure of Aspergillus niger pH 2.5 acid phosphatase at 2. 4 A resolution., Kostrewa D, Wyss M, D'Arcy A, van Loon AP, J Mol Biol. 1999 May 21;288(5):965-74. PMID:10329192

Page seeded by OCA on Thu Mar 20 13:36:54 2008

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