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3muk

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{{STRUCTURE_3muk| PDB=3muk | SCENE= }}
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==Crystal structure of Brd4 bromodomain 1 with propionylated histone H3-K(prop)23==
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===Crystal structure of Brd4 bromodomain 1 with propionylated histone H3-K(prop)23===
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<StructureSection load='3muk' size='340' side='right' caption='[[3muk]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[3muk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MUK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MUK FirstGlance]. <br>
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[[http://www.uniprot.org/uniprot/BRD4_MOUSE BRD4_MOUSE]] Plays a role in a process governing chromosomal dynamics during mitosis.<ref>PMID:10938129</ref>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PRK:N~6~-PROPANOYL-L-LYSINE'>PRK</scene></td></tr>
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==About this Structure==
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3jvk|3jvk]], [[3jvj|3jvj]], [[3mul|3mul]]</td></tr>
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[[3muk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MUK OCA].
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Brd4, Mcap ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3muk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3muk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3muk RCSB], [http://www.ebi.ac.uk/pdbsum/3muk PDBsum]</span></td></tr>
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==Reference==
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</table>
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<ref group="xtra">PMID:020715035</ref><references group="xtra"/><references/>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mu/3muk_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Geyer, M.]]
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[[Category: Geyer, M]]
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[[Category: Vollmuth, F.]]
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[[Category: Vollmuth, F]]
[[Category: Acylation]]
[[Category: Acylation]]
[[Category: Bromodomain]]
[[Category: Bromodomain]]

Revision as of 16:11, 18 December 2014

Crystal structure of Brd4 bromodomain 1 with propionylated histone H3-K(prop)23

3muk, resolution 1.75Å

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