3l0u

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{{STRUCTURE_3l0u| PDB=3l0u | SCENE= }}
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==The crystal structure of unmodified tRNAPhe from Escherichia coli==
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===The crystal structure of unmodified tRNAPhe from Escherichia coli===
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<StructureSection load='3l0u' size='340' side='right' caption='[[3l0u]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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{{ABSTRACT_PUBMED_20203084}}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3l0u]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L0U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3L0U FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3l0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l0u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3l0u RCSB], [http://www.ebi.ac.uk/pdbsum/3l0u PDBsum]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Post-transcriptional nucleoside modifications fine-tune the biophysical and biochemical properties of transfer RNA (tRNA) so that it is optimized for participation in cellular processes. Here we report the crystal structure of unmodified tRNA(Phe) from Escherichia coli at a resolution of 3 A. We show that in the absence of modifications the overall fold of the tRNA is essentially the same as that of mature tRNA. However, there are a number of significant structural differences, such as rearrangements in a triplet base pair and a widened angle between the acceptor and anticodon stems. Contrary to previous observations, the anticodon adopts the same conformation as seen in mature tRNA.
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==About this Structure==
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The crystal structure of unmodified tRNAPhe from Escherichia coli.,Byrne RT, Konevega AL, Rodnina MV, Antson AA Nucleic Acids Res. 2010 Jul 1;38(12):4154-62. Epub 2010 Mar 4. PMID:20203084<ref>PMID:20203084</ref>
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[[3l0u]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L0U OCA].
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==Reference==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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<ref group="xtra">PMID:020203084</ref><references group="xtra"/><references/>
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</div>
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[[Category: Antson, A A.]]
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== References ==
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[[Category: Byrne, R T.]]
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<references/>
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[[Category: Konevega, A L.]]
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__TOC__
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[[Category: Rodnina, M V.]]
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</StructureSection>
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[[Category: Antson, A A]]
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[[Category: Byrne, R T]]
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[[Category: Konevega, A L]]
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[[Category: Rodnina, M V]]
[[Category: Rna]]
[[Category: Rna]]
[[Category: Transcript]]
[[Category: Transcript]]

Revision as of 17:07, 18 December 2014

The crystal structure of unmodified tRNAPhe from Escherichia coli

3l0u, resolution 3.00Å

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