3l32
From Proteopedia
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| - | + | ==Structure of the dimerisation domain of the rabies virus phosphoprotein== | |
| - | + | <StructureSection load='3l32' size='340' side='right' caption='[[3l32]], [[Resolution|resolution]] 1.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| + | <table><tr><td colspan='2'>[[3l32]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rabies_virus Rabies virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L32 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3L32 FirstGlance]. <br> | ||
| + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">P ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11292 Rabies virus])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3l32 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l32 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3l32 RCSB], [http://www.ebi.ac.uk/pdbsum/3l32 PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l3/3l32_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The crystal structure of the dimerization domain of rabies virus phosphoprotein was determined. The monomer consists of two alpha-helices that make a helical hairpin held together mainly by hydrophobic interactions. The monomer has a hydrophilic and a hydrophobic face, and in the dimer two monomers pack together through their hydrophobic surfaces. This structure is very different from the dimerization domain of the vesicular stomatitis virus phosphoprotein and also from the tetramerization domain of the Sendai virus phosphoprotein, suggesting that oligomerization is conserved but not structure. | ||
| - | + | Structure of the dimerization domain of the rabies virus phosphoprotein.,Ivanov I, Crepin T, Jamin M, Ruigrok RW J Virol. 2010 Apr;84(7):3707-10. Epub 2010 Jan 20. PMID:20089657<ref>PMID:20089657</ref> | |
| - | + | ||
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | == References == | |
| - | == | + | <references/> |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
[[Category: Rabies virus]] | [[Category: Rabies virus]] | ||
| - | [[Category: Crepin, T | + | [[Category: Crepin, T]] |
| - | [[Category: Ivanov, I | + | [[Category: Ivanov, I]] |
| - | [[Category: Jamin, M | + | [[Category: Jamin, M]] |
| - | [[Category: Ruigrok, R W.H | + | [[Category: Ruigrok, R W.H]] |
[[Category: Antiparallel alpha-helice]] | [[Category: Antiparallel alpha-helice]] | ||
[[Category: Dimerisation domain]] | [[Category: Dimerisation domain]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| - | [[Category: Rabies virus]] | ||
[[Category: Viral protein]] | [[Category: Viral protein]] | ||
Revision as of 17:32, 18 December 2014
Structure of the dimerisation domain of the rabies virus phosphoprotein
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