3irc

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m (Protected "3irc" [edit=sysop:move=sysop])
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{{STRUCTURE_3irc| PDB=3irc | SCENE= }}
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==Crystal structure analysis of dengue-1 envelope protein domain III==
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===Crystal structure analysis of dengue-1 envelope protein domain III===
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<StructureSection load='3irc' size='340' side='right' caption='[[3irc]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[3irc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Dengue_virus_1 Dengue virus 1]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3egp 3egp]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IRC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3IRC FirstGlance]. <br>
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[[http://www.uniprot.org/uniprot/Q9J7C6_9FLAV Q9J7C6_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774]
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ENVELOPE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11053 Dengue virus 1])</td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3irc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3irc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3irc RCSB], [http://www.ebi.ac.uk/pdbsum/3irc PDBsum], [http://www.topsan.org/Proteins/CSGID/3irc TOPSAN]</span></td></tr>
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[[3irc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Dengue_virus_1 Dengue virus 1]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3egp 3egp]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IRC OCA].
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</table>
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__TOC__
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</StructureSection>
[[Category: Dengue virus 1]]
[[Category: Dengue virus 1]]
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[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
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[[Category: Structural genomic]]
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[[Category: Chruszcz, M.]]
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[[Category: Chruszcz, M]]
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[[Category: Fremont, D H.]]
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[[Category: Fremont, D H]]
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[[Category: Kim, T.]]
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[[Category: Kim, T]]
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[[Category: Minor, W.]]
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[[Category: Minor, W]]
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[[Category: Nelson, C A.]]
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[[Category: Nelson, C A]]
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[[Category: Warren, J T.]]
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[[Category: Warren, J T]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
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[[Category: Center for structural genomics of infectious disease]]
 
[[Category: Csgid]]
[[Category: Csgid]]
[[Category: Envelope]]
[[Category: Envelope]]
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[[Category: Nucleotide-binding]]
[[Category: Nucleotide-binding]]
[[Category: Rna replication]]
[[Category: Rna replication]]
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[[Category: Structural genomic]]
 
[[Category: Transmembrane]]
[[Category: Transmembrane]]
[[Category: Viral protein]]
[[Category: Viral protein]]
[[Category: Virion]]
[[Category: Virion]]
[[Category: Virus]]
[[Category: Virus]]

Revision as of 17:39, 18 December 2014

Crystal structure analysis of dengue-1 envelope protein domain III

3irc, resolution 2.25Å

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