This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3lm0
From Proteopedia
(Difference between revisions)
m (Protected "3lm0" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | + | ==Crystal Structure of human Serine/Threonine Kinase 17B (STK17B)== | |
| - | + | <StructureSection load='3lm0' size='340' side='right' caption='[[3lm0]], [[Resolution|resolution]] 2.35Å' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3lm0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LM0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LM0 FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EBD:[4-({4-[(5-CYCLOPROPYL-1H-PYRAZOL-3-YL)AMINO]-5-METHYLPYRIMIDIN-2-YL}AMINO)PHENYL]ACETONITRILE'>EBD</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3eha|3eha]], [[3lm5|3lm5]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DRAK2, STK17B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lm0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lm0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lm0 RCSB], [http://www.ebi.ac.uk/pdbsum/3lm0 PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lm/3lm0_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | [[ | + | *[[Serine/threonine protein kinase|Serine/threonine protein kinase]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
| - | [[Category: Arrowsmith, C H | + | [[Category: Arrowsmith, C H]] |
| - | [[Category: Bountra, C | + | [[Category: Bountra, C]] |
| - | [[Category: Chaikuad, A | + | [[Category: Chaikuad, A]] |
| - | [[Category: Delft, F von | + | [[Category: Delft, F von]] |
| - | [[Category: Edwards, A | + | [[Category: Edwards, A]] |
| - | [[Category: Fedorov, O | + | [[Category: Fedorov, O]] |
| - | [[Category: Filippakopoulos, P | + | [[Category: Filippakopoulos, P]] |
| - | [[Category: Hapka, E | + | [[Category: Hapka, E]] |
| - | [[Category: Knapp, S | + | [[Category: Knapp, S]] |
| - | [[Category: Phillips, C | + | [[Category: Phillips, C]] |
| - | [[Category: Pike, A C.W | + | [[Category: Pike, A C.W]] |
| - | [[Category: Rellos, P | + | [[Category: Rellos, P]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Soundararajan, M | + | [[Category: Soundararajan, M]] |
| - | [[Category: Ugochukwu, E | + | [[Category: Ugochukwu, E]] |
| - | [[Category: Wang, J | + | [[Category: Wang, J]] |
| - | [[Category: Weigelt, J | + | [[Category: Weigelt, J]] |
[[Category: Apoptosis]] | [[Category: Apoptosis]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
| Line 42: | Line 56: | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
[[Category: Stk17b]] | [[Category: Stk17b]] | ||
| - | [[Category: Structural genomic]] | ||
| - | [[Category: Structural genomics consortium]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 17:41, 18 December 2014
Crystal Structure of human Serine/Threonine Kinase 17B (STK17B)
| |||||||||||
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Arrowsmith, C H | Bountra, C | Chaikuad, A | Delft, F von | Edwards, A | Fedorov, O | Filippakopoulos, P | Hapka, E | Knapp, S | Phillips, C | Pike, A C.W | Rellos, P | Structural genomic | Soundararajan, M | Ugochukwu, E | Wang, J | Weigelt, J | Apoptosis | Atp-binding | Dap kinase related apoptosis-inducing protein kinase 2 | Death-associated protein kinase-related 2 | Drak2 | Kinase | Nucleotide-binding | Nucleus | Phosphoprotein | Serine/threonine kinase 17b | Serine/threonine-protein kinase | Sgc | Stk17b | Transferase
