1qp1
From Proteopedia
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| - | [[Image:1qp1.jpg|left|200px]] | + | [[Image:1qp1.jpg|left|200px]] |
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| - | '''KAPPA VARIABLE LIGHT CHAIN''' | + | {{Structure |
| + | |PDB= 1qp1 |SIZE=350|CAPTION= <scene name='initialview01'>1qp1</scene>, resolution 2.06Å | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''KAPPA VARIABLE LIGHT CHAIN''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1QP1 is a [ | + | 1QP1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QP1 OCA]. |
==Reference== | ==Reference== | ||
| - | Molecular structure of the amyloid-forming protein kappa I Bre., Steinrauf LK, Chiang MY, Shiuan D, J Biochem. 1999 Feb;125(2):422-9. PMID:[http:// | + | Molecular structure of the amyloid-forming protein kappa I Bre., Steinrauf LK, Chiang MY, Shiuan D, J Biochem. 1999 Feb;125(2):422-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9990143 9990143] |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: double spiral]] | [[Category: double spiral]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:40:48 2008'' |
Revision as of 11:40, 20 March 2008
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| , resolution 2.06Å | |||||||
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| Coordinates: | save as pdb, mmCIF, xml | ||||||
KAPPA VARIABLE LIGHT CHAIN
Overview
The molecular structure of the amyloid-forming Bence-Jones protein kappa I Bre has been determined by X-ray crystallography at 2.0 A resolution. The fragment from the kappa chain of immunoprotein contains 107 amino acid residues, and polymerizes in the crystal form into a giant helical spiral, surrounding a cylinder of water 50 A in diameter with a repeat of 77.56 A, containing 12 kappa molecules, plus another 12 molecules from neighboring parallel spirals. The resulting structure has many features which have been found or suggested from studies on the protein fibrils found in amyloid deposits. From the results of the X-ray crystal structure a hypothesis is presented for the structure and formation of the amyloid fibril.
About this Structure
1QP1 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Molecular structure of the amyloid-forming protein kappa I Bre., Steinrauf LK, Chiang MY, Shiuan D, J Biochem. 1999 Feb;125(2):422-9. PMID:9990143
Page seeded by OCA on Thu Mar 20 13:40:48 2008
