3l9k

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{{STRUCTURE_3l9k| PDB=3l9k | SCENE= }}
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==Insights into dynein assembly from a dynein intermediate chain-light chain roadblock structure==
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===Insights into dynein assembly from a dynein intermediate chain-light chain roadblock structure===
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<StructureSection load='3l9k' size='340' side='right' caption='[[3l9k]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[3l9k]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L9K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3L9K FirstGlance]. <br>
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[[http://www.uniprot.org/uniprot/DYIN_DROME DYIN_DROME]] Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the help dynein bind to dynactin 150 kDa component (By similarity).<ref>PMID:11071907</ref>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3l7h|3l7h]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">robl, CG10751, Dmel_CG10751 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 Drosophila melanogaster]), sw, Cdic, Dic19B, CG18000 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 Drosophila melanogaster])</td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3l9k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l9k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3l9k RCSB], [http://www.ebi.ac.uk/pdbsum/3l9k PDBsum]</span></td></tr>
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[[3l9k]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L9K OCA].
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</table>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l9/3l9k_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[Dynein|Dynein]]
*[[Dynein|Dynein]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:020472935</ref><references group="xtra"/><references/>
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[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
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[[Category: Barbar, E.]]
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[[Category: Barbar, E]]
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[[Category: Hall, J.]]
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[[Category: Hall, J]]
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[[Category: Karplus, P A.]]
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[[Category: Karplus, P A]]
[[Category: Dynein]]
[[Category: Dynein]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]

Revision as of 17:51, 18 December 2014

Insights into dynein assembly from a dynein intermediate chain-light chain roadblock structure

3l9k, resolution 3.00Å

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