1qqt
From Proteopedia
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| - | [[Image:1qqt.gif|left|200px]] | + | [[Image:1qqt.gif|left|200px]] |
| - | + | ||
| - | '''METHIONYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI''' | + | {{Structure |
| + | |PDB= 1qqt |SIZE=350|CAPTION= <scene name='initialview01'>1qqt</scene>, resolution 2.03Å | ||
| + | |SITE= | ||
| + | |LIGAND= <scene name='pdbligand=ZN:ZINC ION'>ZN</scene> | ||
| + | |ACTIVITY= [http://en.wikipedia.org/wiki/Methionine--tRNA_ligase Methionine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.10 6.1.1.10] | ||
| + | |GENE= | ||
| + | }} | ||
| + | |||
| + | '''METHIONYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1QQT is a [ | + | 1QQT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QQT OCA]. |
==Reference== | ==Reference== | ||
| - | Crystal structure of Escherichia coli methionyl-tRNA synthetase highlights species-specific features., Mechulam Y, Schmitt E, Maveyraud L, Zelwer C, Nureki O, Yokoyama S, Konno M, Blanquet S, J Mol Biol. 1999 Dec 17;294(5):1287-97. PMID:[http:// | + | Crystal structure of Escherichia coli methionyl-tRNA synthetase highlights species-specific features., Mechulam Y, Schmitt E, Maveyraud L, Zelwer C, Nureki O, Yokoyama S, Konno M, Blanquet S, J Mol Biol. 1999 Dec 17;294(5):1287-97. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10600385 10600385] |
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Methionine--tRNA ligase]] | [[Category: Methionine--tRNA ligase]] | ||
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[[Category: trna ligase]] | [[Category: trna ligase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:41:28 2008'' |
Revision as of 11:41, 20 March 2008
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| , resolution 2.03Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | |||||||
| Activity: | Methionine--tRNA ligase, with EC number 6.1.1.10 | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
METHIONYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI
Overview
The 3D structure of monomeric C-truncated Escherichia coli methionyl-tRNA synthetase, a class 1 aminoacyl-tRNA synthetase, has been solved at 2.0 A resolution. Remarkably, the polypeptide connecting the two halves of the Rossmann fold exposes two identical knuckles related by a 2-fold axis but with zinc in the distal knuckle only. Examination of available MetRS orthologs reveals four classes according to the number and zinc content of the putative knuckles. Extreme cases are exemplified by the MetRS of eucaryotic or archaeal origin, where two knuckles and two metal ions are expected, and by the mitochondrial enzymes, which are predicted to have one knuckle without metal ion.
About this Structure
1QQT is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
Crystal structure of Escherichia coli methionyl-tRNA synthetase highlights species-specific features., Mechulam Y, Schmitt E, Maveyraud L, Zelwer C, Nureki O, Yokoyama S, Konno M, Blanquet S, J Mol Biol. 1999 Dec 17;294(5):1287-97. PMID:10600385
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