This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3lp6
From Proteopedia
(Difference between revisions)
m (Protected "3lp6" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | + | ==Crystal Structure of Rv3275c-E60A from Mycobacterium tuberculosis at 1.7A resolution== | |
| - | + | <StructureSection load='3lp6' size='340' side='right' caption='[[3lp6]], [[Resolution|resolution]] 1.70Å' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3lp6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LP6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LP6 FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MT3375, MTCY71.15c, purE, Rv3275c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoribosylaminoimidazole_carboxylase Phosphoribosylaminoimidazole carboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.21 4.1.1.21] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lp6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lp6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lp6 RCSB], [http://www.ebi.ac.uk/pdbsum/3lp6 PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lp/3lp6_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | [[ | + | *[[Phosphoribosylaminoimidazole carboxylase|Phosphoribosylaminoimidazole carboxylase]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: Phosphoribosylaminoimidazole carboxylase]] | [[Category: Phosphoribosylaminoimidazole carboxylase]] | ||
| - | [[Category: Hung, L W | + | [[Category: Hung, L W]] |
| - | [[Category: ISFI, Integrated Center for Structure and Function Innovation | + | [[Category: ISFI, Integrated Center for Structure and Function Innovation]] |
| - | [[Category: Kim, C Y | + | [[Category: Kim, C Y]] |
| - | [[Category: Kim, H | + | [[Category: Kim, H]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Terwilliger, T C | + | [[Category: Terwilliger, T C]] |
| - | [[Category: Yu, M | + | [[Category: Yu, M]] |
[[Category: Alpha and beta protein]] | [[Category: Alpha and beta protein]] | ||
[[Category: Decarboxylase]] | [[Category: Decarboxylase]] | ||
| Line 21: | Line 37: | ||
[[Category: Isfi]] | [[Category: Isfi]] | ||
[[Category: Lyase]] | [[Category: Lyase]] | ||
| - | [[Category: Protein structure initiative | + | [[Category: PSI, Protein structure initiative]] |
| - | + | ||
[[Category: Purine biosynthesis]] | [[Category: Purine biosynthesis]] | ||
| - | [[Category: Structural genomic]] | ||
| - | [[Category: Tb structural genomics consortium]] | ||
[[Category: Tbsgc]] | [[Category: Tbsgc]] | ||
Revision as of 18:03, 18 December 2014
Crystal Structure of Rv3275c-E60A from Mycobacterium tuberculosis at 1.7A resolution
| |||||||||||
Categories: Mycobacterium tuberculosis | Phosphoribosylaminoimidazole carboxylase | Hung, L W | ISFI, Integrated Center for Structure and Function Innovation | Kim, C Y | Kim, H | Structural genomic | Terwilliger, T C | Yu, M | Alpha and beta protein | Decarboxylase | Integrated center for structure and function innovation | Isfi | Lyase | PSI, Protein structure initiative | Purine biosynthesis | Tbsgc
