3noi

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{{STRUCTURE_3noi| PDB=3noi | SCENE= }}
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==Crystal Structure of Natural Killer Cell Cytotoxicity Receptor NKp30 (NCR3)==
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===Crystal Structure of Natural Killer Cell Cytotoxicity Receptor NKp30 (NCR3)===
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<StructureSection load='3noi' size='340' side='right' caption='[[3noi]], [[Resolution|resolution]] 1.84&Aring;' scene=''>
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{{ABSTRACT_PUBMED_021444796}}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3noi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NOI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NOI FirstGlance]. <br>
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==Function==
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PG:2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL'>1PG</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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[[http://www.uniprot.org/uniprot/NCTR3_HUMAN NCTR3_HUMAN]] Cytotoxicity-activating receptor that contributes to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.<ref>PMID:10562324</ref> <ref>PMID:15784725</ref> <ref>PMID:18852879</ref>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NKp30, 1C7, LY117, NCR3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3noi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3noi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3noi RCSB], [http://www.ebi.ac.uk/pdbsum/3noi PDBsum]</span></td></tr>
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==About this Structure==
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</table>
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[[3noi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NOI OCA].
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__TOC__
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</StructureSection>
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==Reference==
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<references group="xtra"/><references/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Joyce, M G.]]
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[[Category: Joyce, M G]]
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[[Category: Sun, P D.]]
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[[Category: Sun, P D]]
[[Category: Immune system]]
[[Category: Immune system]]
[[Category: Immunoglobulin-like i2 type domain]]
[[Category: Immunoglobulin-like i2 type domain]]

Revision as of 06:58, 19 December 2014

Crystal Structure of Natural Killer Cell Cytotoxicity Receptor NKp30 (NCR3)

3noi, resolution 1.84Å

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