3o46

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{{STRUCTURE_3o46| PDB=3o46 | SCENE= }}
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==Crystal structure of the PDZ domain of MPP7==
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===Crystal structure of the PDZ domain of MPP7===
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<StructureSection load='3o46' size='340' side='right' caption='[[3o46]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[3o46]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O46 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3O46 FirstGlance]. <br>
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[[http://www.uniprot.org/uniprot/MPP7_HUMAN MPP7_HUMAN]] Acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. Involved in the assembly of protein complexes at sites of cell-cell contact.<ref>PMID:17332497</ref>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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==About this Structure==
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MPP7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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[[3o46]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O46 OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3o46 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o46 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3o46 RCSB], [http://www.ebi.ac.uk/pdbsum/3o46 PDBsum]</span></td></tr>
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</table>
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==Reference==
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== Evolutionary Conservation ==
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<references group="xtra"/><references/>
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o4/3o46_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Arrowsmith, C H]]
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[[Category: Bochkarev, A.]]
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[[Category: Bochkarev, A]]
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[[Category: Bountra, C.]]
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[[Category: Bountra, C]]
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[[Category: Edwards, A M.]]
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[[Category: Edwards, A M]]
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[[Category: Guan, X.]]
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[[Category: Guan, X]]
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[[Category: Landry, R.]]
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[[Category: Landry, R]]
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[[Category: Nedyalkova, L.]]
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[[Category: Nedyalkova, L]]
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[[Category: Park, H.]]
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[[Category: Park, H]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Structural genomic]]
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[[Category: Tempel, W.]]
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[[Category: Tempel, W]]
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[[Category: Tong, Y.]]
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[[Category: Tong, Y]]
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[[Category: Weigelt, J.]]
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[[Category: Weigelt, J]]
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[[Category: Zhong, N.]]
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[[Category: Zhong, N]]
[[Category: Pdz domain]]
[[Category: Pdz domain]]
[[Category: Protein binding]]
[[Category: Protein binding]]
[[Category: Sgc]]
[[Category: Sgc]]
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[[Category: Structural genomics consortium]]
 

Revision as of 07:18, 19 December 2014

Crystal structure of the PDZ domain of MPP7

3o46, resolution 1.30Å

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