This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3oa1

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "3oa1" [edit=sysop:move=sysop])
Line 1: Line 1:
-
{{STRUCTURE_3oa1| PDB=3oa1 | SCENE= }}
+
==Crystal structure of phosphoprotein/Protein P/Protein M1 residues 69-297 from Rabies virus reveals degradation to C-terminal domain only==
-
===Crystal structure of phosphoprotein/Protein P/Protein M1 residues 69-297 from Rabies virus reveals degradation to C-terminal domain only===
+
<StructureSection load='3oa1' size='340' side='right' caption='[[3oa1]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-
 
+
== Structural highlights ==
-
==Function==
+
<table><tr><td colspan='2'>[[3oa1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rabies_virus_strain_pasteur_vaccin Rabies virus strain pasteur vaccin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OA1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OA1 FirstGlance]. <br>
-
[[http://www.uniprot.org/uniprot/PHOSP_RABVP PHOSP_RABVP]] Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication. Stabilizes the RNA polymerase L to the N-RNA template and binds the soluble protein N, preventing it from encapsidating non-genomic RNA. Also inhibits host IFN-alpha and IFN-beta signaling by binding and retaining phosphorylated STAT1 in the cytoplasm or by inhibiting the DNA binding of STAT1 in the nucleus. Might be involved, through interaction with host dynein, in intracellular microtubule-dependent virus transport of incoming virus from the synapse toward the cell body (By similarity).
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
 
+
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1vyi|1vyi]], [[3l32|3l32]]</td></tr>
-
==About this Structure==
+
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">P ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=103929 Rabies virus strain Pasteur vaccin])</td></tr>
-
[[3oa1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rabies_virus_strain_pasteur_vaccin Rabies virus strain pasteur vaccin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OA1 OCA].
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3oa1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3oa1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3oa1 RCSB], [http://www.ebi.ac.uk/pdbsum/3oa1 PDBsum]</span></td></tr>
 +
</table>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oa/3oa1_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
 +
<div style="clear:both"></div>
 +
__TOC__
 +
</StructureSection>
[[Category: Rabies virus strain pasteur vaccin]]
[[Category: Rabies virus strain pasteur vaccin]]
-
[[Category: SSGCID, Seattle Structural Genomics Center for Infectious Disease.]]
+
[[Category: Structural genomic]]
[[Category: Chaperone]]
[[Category: Chaperone]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
Line 14: Line 27:
[[Category: Rabies virus]]
[[Category: Rabies virus]]
[[Category: Rabies virus protein n]]
[[Category: Rabies virus protein n]]
-
[[Category: Seattle structural genomics center for infectious disease]]
 
[[Category: Ssgcid]]
[[Category: Ssgcid]]

Revision as of 07:23, 19 December 2014

Crystal structure of phosphoprotein/Protein P/Protein M1 residues 69-297 from Rabies virus reveals degradation to C-terminal domain only

3oa1, resolution 2.20Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3oa1"
Personal tools