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3qf9
From Proteopedia
(Difference between revisions)
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| - | + | ==Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a furan-thiazolidinedione ligand== | |
| - | + | <StructureSection load='3qf9' size='340' side='right' caption='[[3qf9]], [[Resolution|resolution]] 2.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[3qf9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QF9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QF9 FirstGlance]. <br> |
| - | [[http:// | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NM8:6-{5-[(Z)-(2,4-DIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}-N-{3-[(4-ETHYLPIPERAZIN-1-YL)METHYL]-5-(TRIFLUOROMETHYL)PHENYL}NAPHTHALENE-1-CARBOXAMIDE'>NM8</scene></td></tr> |
| - | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PIM1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | |
| - | == | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qf9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qf9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qf9 RCSB], [http://www.ebi.ac.uk/pdbsum/3qf9 PDBsum]</span></td></tr> | |
| + | </table> | ||
==See Also== | ==See Also== | ||
*[[Proto-oncogene serine/threonine-protein kinase|Proto-oncogene serine/threonine-protein kinase]] | *[[Proto-oncogene serine/threonine-protein kinase|Proto-oncogene serine/threonine-protein kinase]] | ||
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
| - | [[Category: Arrowsmith, C H | + | [[Category: Arrowsmith, C H]] |
| - | [[Category: Bountra, C | + | [[Category: Bountra, C]] |
| - | [[Category: Bullock, A N | + | [[Category: Bullock, A N]] |
| - | [[Category: Delft, F von | + | [[Category: Delft, F von]] |
| - | [[Category: Edwards, A | + | [[Category: Edwards, A]] |
| - | [[Category: Fedorov, O | + | [[Category: Fedorov, O]] |
| - | [[Category: Filippakopoulos, P | + | [[Category: Filippakopoulos, P]] |
| - | [[Category: Grey, N | + | [[Category: Grey, N]] |
| - | [[Category: Knapp, S | + | [[Category: Knapp, S]] |
| - | [[Category: Miduturu, C V | + | [[Category: Miduturu, C V]] |
| - | [[Category: Weigelt, J | + | [[Category: Weigelt, J]] |
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Cancer]] | [[Category: Cancer]] | ||
| Line 38: | Line 38: | ||
[[Category: Serine/threonine-protein kinase]] | [[Category: Serine/threonine-protein kinase]] | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
| - | [[Category: Structural | + | [[Category: Structural genomic]] |
[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Transferase-transferase inhibitor complex]] | [[Category: Transferase-transferase inhibitor complex]] | ||
[[Category: Transferase/peptide]] | [[Category: Transferase/peptide]] | ||
Revision as of 10:24, 19 December 2014
Crystal structure of human proto-oncogene serine threonine kinase (PIM1) in complex with a consensus peptide and a furan-thiazolidinedione ligand
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Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Arrowsmith, C H | Bountra, C | Bullock, A N | Delft, F von | Edwards, A | Fedorov, O | Filippakopoulos, P | Grey, N | Knapp, S | Miduturu, C V | Weigelt, J | Atp-binding | Cancer | Complex transferase-peptide | Kinase | Leukemia | Nuclear protein | Nucleotide-binding | Phosphorylation | Pim1 | Proto-oncogene | Serine/threonine-protein kinase | Sgc | Structural genomic | Transferase | Transferase-transferase inhibitor complex | Transferase/peptide
