3qr5

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
{{STRUCTURE_3qr5| PDB=3qr5 | SCENE= }}
+
==Structure of the first domain of a cardiac Ryanodine Receptor mutant with exon 3 deleted==
-
===Structure of the first domain of a cardiac Ryanodine Receptor mutant with exon 3 deleted===
+
<StructureSection load='3qr5' size='340' side='right' caption='[[3qr5]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-
 
+
== Structural highlights ==
-
==Function==
+
<table><tr><td colspan='2'>[[3qr5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QR5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QR5 FirstGlance]. <br>
-
[[http://www.uniprot.org/uniprot/Q9ERN6_MOUSE Q9ERN6_MOUSE]] Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca(2+) levels due to activation of the L-type calcium channel CACNA1C. The calcium channel activity is modulated by formation of heterotetramers with RYR3. Required for cellular calcium ion homeostasis. Required for embryonic heart development.<ref>PMID:10473538</ref> <ref>PMID:9628868</ref> <ref>PMID:21098440</ref> <ref>PMID:20431056</ref>
+
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3im5|3im5]]</td></tr>
-
 
+
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Ryr2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qr5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qr5 RCSB], [http://www.ebi.ac.uk/pdbsum/3qr5 PDBsum]</span></td></tr>
-
[[3qr5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QR5 OCA].
+
</table>
-
 
+
__TOC__
-
==Reference==
+
</StructureSection>
-
<references group="xtra"/><references/>
+
[[Category: Mus musculus]]
[[Category: Mus musculus]]
-
[[Category: Lobo, P A.]]
+
[[Category: Lobo, P A]]
-
[[Category: Petegem, F Van.]]
+
[[Category: Petegem, F Van]]
[[Category: Beta trefoil]]
[[Category: Beta trefoil]]
[[Category: Sarcoplasmic reticulum]]
[[Category: Sarcoplasmic reticulum]]
[[Category: Signaling protein]]
[[Category: Signaling protein]]

Revision as of 10:35, 19 December 2014

Structure of the first domain of a cardiac Ryanodine Receptor mutant with exon 3 deleted

3qr5, resolution 2.30Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3qr5"
Personal tools