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3pv6

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{{STRUCTURE_3pv6| PDB=3pv6 | SCENE= }}
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==Crystal structure of NKp30 bound to its ligand B7-H6==
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===Crystal structure of NKp30 bound to its ligand B7-H6===
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<StructureSection load='3pv6' size='340' side='right' caption='[[3pv6]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[3pv6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PV6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PV6 FirstGlance]. <br>
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[[http://www.uniprot.org/uniprot/NCTR3_HUMAN NCTR3_HUMAN]] Cytotoxicity-activating receptor that contributes to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.<ref>PMID:10562324</ref> <ref>PMID:15784725</ref> <ref>PMID:18852879</ref>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3pv7|3pv7]]</td></tr>
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==About this Structure==
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NCR3, 1C7, LY117 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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[[3pv6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PV6 OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pv6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pv6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pv6 RCSB], [http://www.ebi.ac.uk/pdbsum/3pv6 PDBsum]</span></td></tr>
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</table>
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==Reference==
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__TOC__
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<references group="xtra"/><references/>
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Li, Y.]]
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[[Category: Li, Y]]
[[Category: Immune system]]
[[Category: Immune system]]
[[Category: Nk cell receptor]]
[[Category: Nk cell receptor]]
[[Category: Receptor-ligand complex]]
[[Category: Receptor-ligand complex]]

Revision as of 10:38, 19 December 2014

Crystal structure of NKp30 bound to its ligand B7-H6

3pv6, resolution 2.30Å

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