3q90

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{{STRUCTURE_3q90| PDB=3q90 | SCENE= }}
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==Crystal structure of the NTF2 domain of Ras GTPase-activating protein-binding protein 1==
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===Crystal structure of the NTF2 domain of Ras GTPase-activating protein-binding protein 1===
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<StructureSection load='3q90' size='340' side='right' caption='[[3q90]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[3q90]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q90 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q90 FirstGlance]. <br>
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[[http://www.uniprot.org/uniprot/G3BP1_HUMAN G3BP1_HUMAN]] May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.<ref>PMID:9889278</ref> <ref>PMID:11604510</ref>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3q91|3q91]], [[3q93|3q93]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">G3BP, G3BP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q90 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q90 RCSB], [http://www.ebi.ac.uk/pdbsum/3q90 PDBsum]</span></td></tr>
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[[3q90]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q90 OCA].
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</table>
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__TOC__
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==Reference==
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</StructureSection>
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<references group="xtra"/><references/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Arrowsmith, C H]]
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[[Category: Berg, S Van Der.]]
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[[Category: Berg, S Van Der]]
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[[Category: Berglund, H.]]
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[[Category: Berglund, H]]
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[[Category: Bountra, C.]]
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[[Category: Bountra, C]]
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[[Category: Collins, R.]]
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[[Category: Collins, R]]
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[[Category: Edwards, A M.]]
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[[Category: Edwards, A M]]
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[[Category: Ekblad, T.]]
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[[Category: Ekblad, T]]
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[[Category: Flodin, S.]]
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[[Category: Flodin, S]]
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[[Category: Flores, A.]]
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[[Category: Flores, A]]
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[[Category: Graslund, S.]]
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[[Category: Graslund, S]]
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[[Category: Hammarstrom, M.]]
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[[Category: Hammarstrom, M]]
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[[Category: Johansson, I.]]
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[[Category: Johansson, I]]
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[[Category: Karlberg, T.]]
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[[Category: Karlberg, T]]
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[[Category: Kol, S.]]
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[[Category: Kol, S]]
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[[Category: Kotenyova, T.]]
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[[Category: Kotenyova, T]]
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[[Category: Kouznetsova, E.]]
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[[Category: Kouznetsova, E]]
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[[Category: Moche, M.]]
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[[Category: Moche, M]]
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[[Category: Nordlund, P.]]
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[[Category: Nordlund, P]]
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[[Category: Nyman, T.]]
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[[Category: Nyman, T]]
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[[Category: Persson, C.]]
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[[Category: Persson, C]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Structural genomic]]
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[[Category: Schuler, H.]]
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[[Category: Schuler, H]]
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[[Category: Schutz, P.]]
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[[Category: Schutz, P]]
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[[Category: Siponen, M I.]]
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[[Category: Siponen, M I]]
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[[Category: Thorsell, A G.]]
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[[Category: Thorsell, A G]]
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[[Category: Tresaugues, L.]]
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[[Category: Tresaugues, L]]
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[[Category: Wahlberg, E.]]
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[[Category: Wahlberg, E]]
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[[Category: Weigelt, J.]]
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[[Category: Weigelt, J]]
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[[Category: Welin, M.]]
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[[Category: Welin, M]]
[[Category: Dna and rna binding]]
[[Category: Dna and rna binding]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
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[[Category: Protein binding and helicase]]
[[Category: Protein binding and helicase]]
[[Category: Sgc]]
[[Category: Sgc]]
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[[Category: Structural genomic]]
 
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[[Category: Structural genomics consortium]]
 

Revision as of 10:42, 19 December 2014

Crystal structure of the NTF2 domain of Ras GTPase-activating protein-binding protein 1

3q90, resolution 1.70Å

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