3q91

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{{STRUCTURE_3q91| PDB=3q91 | SCENE= }}
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==Crystal Structure of Human Uridine Diphosphate Glucose Pyrophosphatase (NUDT14)==
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===Crystal Structure of Human Uridine Diphosphate Glucose Pyrophosphatase (NUDT14)===
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<StructureSection load='3q91' size='340' side='right' caption='[[3q91]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[3q91]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q91 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q91 FirstGlance]. <br>
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[[http://www.uniprot.org/uniprot/NUD14_HUMAN NUD14_HUMAN]] Hydrolyzes UDP-glucose to glucose 1-phosphate and UMP and ADP-ribose to ribose 5-phosphate and AMP. The physiological substrate is probably UDP-glucose. Poor activity on other substrates such as ADP-glucose, CDP-glucose, GDP-glucose and GDP-mannose.
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3q90|3q90]], [[3q93|3q93]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NUDT14, UGPP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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==About this Structure==
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-sugar_diphosphatase UDP-sugar diphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.45 3.6.1.45] </span></td></tr>
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[[3q91]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q91 OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q91 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q91 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q91 RCSB], [http://www.ebi.ac.uk/pdbsum/3q91 PDBsum]</span></td></tr>
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</table>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: UDP-sugar diphosphatase]]
[[Category: UDP-sugar diphosphatase]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Arrowsmith, C H]]
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[[Category: Berg, S Van Der.]]
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[[Category: Berg, S Van Der]]
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[[Category: Berglund, H.]]
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[[Category: Berglund, H]]
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[[Category: Bountra, C.]]
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[[Category: Bountra, C]]
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[[Category: Collins, R.]]
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[[Category: Collins, R]]
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[[Category: Edwards, A M.]]
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[[Category: Edwards, A M]]
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[[Category: Ekblad, T.]]
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[[Category: Ekblad, T]]
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[[Category: Flodin, S.]]
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[[Category: Flodin, S]]
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[[Category: Flores, A.]]
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[[Category: Flores, A]]
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[[Category: Graslund, S.]]
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[[Category: Graslund, S]]
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[[Category: Hammarstrom, M.]]
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[[Category: Hammarstrom, M]]
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[[Category: Johansson, I.]]
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[[Category: Johansson, I]]
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[[Category: Karlberg, T.]]
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[[Category: Karlberg, T]]
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[[Category: Kol, S.]]
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[[Category: Kol, S]]
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[[Category: Kotenyova, T.]]
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[[Category: Kotenyova, T]]
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[[Category: Kouznetsova, E.]]
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[[Category: Kouznetsova, E]]
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[[Category: Moche, M.]]
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[[Category: Moche, M]]
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[[Category: Nordlund, P.]]
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[[Category: Nordlund, P]]
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[[Category: Nyman, T.]]
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[[Category: Nyman, T]]
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[[Category: Persson, C.]]
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[[Category: Persson, C]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Structural genomic]]
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[[Category: Schuler, H.]]
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[[Category: Schuler, H]]
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[[Category: Schutz, P.]]
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[[Category: Schutz, P]]
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[[Category: Siponen, M I.]]
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[[Category: Siponen, M I]]
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[[Category: Thorsell, A G.]]
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[[Category: Thorsell, A G]]
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[[Category: Tresaugues, L.]]
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[[Category: Tresaugues, L]]
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[[Category: Wahlberg, E.]]
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[[Category: Wahlberg, E]]
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[[Category: Weigelt, J.]]
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[[Category: Weigelt, J]]
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[[Category: Welin, M.]]
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[[Category: Welin, M]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Magnesium binding]]
[[Category: Magnesium binding]]
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[[Category: Nudix]]
[[Category: Nudix]]
[[Category: Sgc]]
[[Category: Sgc]]
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[[Category: Structural genomic]]
 
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[[Category: Structural genomics consortium]]
 

Revision as of 10:59, 19 December 2014

Crystal Structure of Human Uridine Diphosphate Glucose Pyrophosphatase (NUDT14)

3q91, resolution 2.70Å

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