3tdg

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
{{STRUCTURE_3tdg| PDB=3tdg | SCENE= }}
+
==Structural and functional characterization of Helicobacter pylori DsbG==
-
===Structural and functional characterization of Helicobacter pylori DsbG===
+
<StructureSection load='3tdg' size='340' side='right' caption='[[3tdg]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
-
{{ABSTRACT_PUBMED_22062156}}
+
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[3tdg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TDG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TDG FirstGlance]. <br>
 +
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene></td></tr>
 +
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HP_0231 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=210 Helicobacter pylori])</td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tdg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tdg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3tdg RCSB], [http://www.ebi.ac.uk/pdbsum/3tdg PDBsum]</span></td></tr>
 +
</table>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
Dsb proteins play important roles in bacterial pathogenicity. To better understand the role of Dsb proteins in Helicobacter pylori, we have structurally and functionally characterized H. pylori DsbG (HP0231). The monomer consists of two domains connected by a helical linker. Two monomers associate to form a V-shaped dimer. The monomeric and dimeric structures of H. pylori DsbG show significant differences compared to Escherichia coli DsbG. Two polyethylene glycol molecules are bound in the cleft of the V-shaped dimer, suggesting a possible role as a chaperone. Furthermore, we show that H. pylori DsbG functions as a reductase against HP0518, a putative L,D-transpeptidase with a catalytic cysteine residue.
-
==About this Structure==
+
Structural and functional characterization of Helicobacter pylori DsbG.,Yoon JY, Kim J, Lee SJ, Kim HS, Im HN, Yoon HJ, Kim KH, Kim SJ, Han BW, Suh SW FEBS Lett. 2011 Dec 15;585(24):3862-7. doi: 10.1016/j.febslet.2011.10.042. Epub, 2011 Nov 2. PMID:22062156<ref>PMID:22062156</ref>
-
[[3tdg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TDG OCA].
+
-
==Reference==
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-
<ref group="xtra">PMID:022062156</ref><references group="xtra"/><references/>
+
</div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
[[Category: Helicobacter pylori]]
[[Category: Helicobacter pylori]]
-
[[Category: Han, B W.]]
+
[[Category: Han, B W]]
-
[[Category: Im, H N.]]
+
[[Category: Im, H N]]
-
[[Category: Kim, H S.]]
+
[[Category: Kim, H S]]
-
[[Category: Kim, J.]]
+
[[Category: Kim, J]]
-
[[Category: Kim, K H.]]
+
[[Category: Kim, K H]]
-
[[Category: Kim, S.]]
+
[[Category: Kim, S]]
-
[[Category: Lee, S J.]]
+
[[Category: Lee, S J]]
-
[[Category: Suh, S W.]]
+
[[Category: Suh, S W]]
-
[[Category: Yoon, H.]]
+
[[Category: Yoon, H]]
-
[[Category: Yoon, J Y.]]
+
[[Category: Yoon, J Y]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: Reductase]]
[[Category: Reductase]]
[[Category: Thioredoxin fold]]
[[Category: Thioredoxin fold]]

Revision as of 06:43, 21 December 2014

Structural and functional characterization of Helicobacter pylori DsbG

3tdg, resolution 2.10Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3tdg"
Personal tools