3v68
From Proteopedia
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| - | + | ==Crystal structure of Pyrococcus furiosus PF2050, a member of DUF2666 family protein== | |
| - | + | <StructureSection load='3v68' size='340' side='right' caption='[[3v68]], [[Resolution|resolution]] 1.56Å' scene=''> | |
| - | + | == Structural highlights == | |
| + | <table><tr><td colspan='2'>[[3v68]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus_dsm_3638 Pyrococcus furiosus dsm 3638]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V68 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3V68 FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PF2050 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=186497 Pyrococcus furiosus DSM 3638])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3v68 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v68 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3v68 RCSB], [http://www.ebi.ac.uk/pdbsum/3v68 PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Pyrococcus furiosus PF2050 is an uncharacterized putative protein that contains two DUF2666 domains. Functional and structural studies of PF2050 have not previously been performed. In this study, we determined the crystal structure of PF2050. The structure of PF2050 showed that the two DUF2666 domains interact tightly, forming a globular structure. Each DUF2666 domain comprises an antiparallel beta-sheet and an alpha-helical bundle. One side of the PF2050 structure has a positively charged basic cleft, which may have a DNA-binding function. Furthermore, we confirmed that PF2050 interacts with circular and linear dsDNA. | ||
| - | + | Crystal structure of Pyrococcus furiosus PF2050, a member of the DUF2666 protein family.,Han BG, Jeong KC, Cho JW, Jeong BC, Song HK, Lee JY, Shin DH, Lee S, Lee BI FEBS Lett. 2012 May 7;586(9):1384-8. doi: 10.1016/j.febslet.2012.04.004. Epub, 2012 Apr 13. PMID:22616997<ref>PMID:22616997</ref> | |
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| - | == | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
| - | + | </div> | |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Pyrococcus furiosus dsm 3638]] | [[Category: Pyrococcus furiosus dsm 3638]] | ||
| - | [[Category: Han, B G | + | [[Category: Han, B G]] |
| - | [[Category: Lee, B I | + | [[Category: Lee, B I]] |
[[Category: Dna binding protein]] | [[Category: Dna binding protein]] | ||
[[Category: Double stranded dna]] | [[Category: Double stranded dna]] | ||
[[Category: Duf2666]] | [[Category: Duf2666]] | ||
Revision as of 06:47, 21 December 2014
Crystal structure of Pyrococcus furiosus PF2050, a member of DUF2666 family protein
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