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1r9g
From Proteopedia
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| - | [[Image:1r9g.jpg|left|200px]] | + | [[Image:1r9g.jpg|left|200px]] |
| - | + | ||
| - | '''Three-dimensional Structure of YaaE from Bacillus subtilis''' | + | {{Structure |
| + | |PDB= 1r9g |SIZE=350|CAPTION= <scene name='initialview01'>1r9g</scene>, resolution 2.5Å | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= YAAE, BSU00120 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus subtilis]) | ||
| + | }} | ||
| + | |||
| + | '''Three-dimensional Structure of YaaE from Bacillus subtilis''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1R9G is a [ | + | 1R9G is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R9G OCA]. |
==Reference== | ==Reference== | ||
| - | Three-dimensional structure of YaaE from Bacillus subtilis, a glutaminase implicated in pyridoxal-5'-phosphate biosynthesis., Bauer JA, Bennett EM, Begley TP, Ealick SE, J Biol Chem. 2004 Jan 23;279(4):2704-11. Epub 2003 Oct 28. PMID:[http:// | + | Three-dimensional structure of YaaE from Bacillus subtilis, a glutaminase implicated in pyridoxal-5'-phosphate biosynthesis., Bauer JA, Bennett EM, Begley TP, Ealick SE, J Biol Chem. 2004 Jan 23;279(4):2704-11. Epub 2003 Oct 28. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14585832 14585832] |
[[Category: Bacillus subtilis]] | [[Category: Bacillus subtilis]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: triad amidotransferase]] | [[Category: triad amidotransferase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:48:31 2008'' |
Revision as of 11:48, 20 March 2008
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| , resolution 2.5Å | |||||||
|---|---|---|---|---|---|---|---|
| Gene: | YAAE, BSU00120 (Bacillus subtilis) | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Three-dimensional Structure of YaaE from Bacillus subtilis
Overview
The structure of YaaE from Bacillus subtilis was determined at 2.5-A resolution. YaaE is a member of the triad glutamine aminotransferase family and functions in a recently identified alternate pathway for the biosynthesis of vitamin B(6). Proposed active residues include conserved Cys-79, His-170, and Glu-172. YaaE shows similarity to HisH, a glutaminase involved in histidine biosynthesis. YaaD associates with YaaE. A homology model of this protein was constructed. YaaD is predicted to be a (beta/alpha)(8) barrel on the basis of sequence comparisons. The predicted active site includes highly conserved residues 211-216 and 233-235. Finally, a homology model of a putative YaaD-YaaE complex was prepared using the structure of HisH-F as a model. This model predicts that the ammonia molecule generated by YaaE is channeled through the center of the YaaD barrel to the putative YaaD active site.
About this Structure
1R9G is a Single protein structure of sequence from Bacillus subtilis. Full crystallographic information is available from OCA.
Reference
Three-dimensional structure of YaaE from Bacillus subtilis, a glutaminase implicated in pyridoxal-5'-phosphate biosynthesis., Bauer JA, Bennett EM, Begley TP, Ealick SE, J Biol Chem. 2004 Jan 23;279(4):2704-11. Epub 2003 Oct 28. PMID:14585832
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