3vsn

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{{STRUCTURE_3vsn| PDB=3vsn | SCENE= }}
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==The crystal structure of novel chondroition lyase ODV-E66, baculovirus envelope protein==
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===The crystal structure of novel chondroition lyase ODV-E66, baculovirus envelope protein===
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<StructureSection load='3vsn' size='340' side='right' caption='[[3vsn]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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{{ABSTRACT_PUBMED_22297996}}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3vsn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Autographa_californica_nucleopolyhedrovirus Autographa californica nucleopolyhedrovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VSN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VSN FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3vsm|3vsm]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">P79 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=46015 Autographa californica nucleopolyhedrovirus])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vsn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vsn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vsn RCSB], [http://www.ebi.ac.uk/pdbsum/3vsn PDBsum]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Baculovirus envelope protein ODV-E66 (67-704), in which the N-terminal 66 amino acids are truncated, is a chondroitin lyase. It digests chondroitin and chondroitin 6-sulfate efficiently, but does not digest chondroitin 4-sulfate. This unique characteristic is useful for the preparation of specific chondroitin oligosaccharides and for investigation of the mechanism of baculovirus infection. ODV-E66 (67-704) was crystallized; the crystal diffracted to 1.8 A resolution and belonged to space group P6(2) or P6(4), with unit-cell parameters a = b = 113.5, c = 101.5 A. One molecule is assumed to be present per asymmetric unit, which gives a Matthews coefficient of 2.54 A(3) Da(-1).
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==Function==
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Crystallization and X-ray diffraction analysis of chondroitin lyase from baculovirus: envelope protein ODV-E66.,Kawaguchi Y, Sugiura N, Onishi M, Kimata K, Kimura M, Kakuta Y Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Feb 1;68(Pt 2):190-2. doi:, 10.1107/S1744309111053164. Epub 2012 Jan 26. PMID:22297996<ref>PMID:22297996</ref>
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[[http://www.uniprot.org/uniprot/OE66_NPVAC OE66_NPVAC]] Component of the polyhedra envelope.
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==About this Structure==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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[[3vsn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Autographa_californica_nucleopolyhedrovirus Autographa californica nucleopolyhedrovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VSN OCA].
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</div>
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:022297996</ref><references group="xtra"/><references/>
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__TOC__
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</StructureSection>
[[Category: Autographa californica nucleopolyhedrovirus]]
[[Category: Autographa californica nucleopolyhedrovirus]]
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[[Category: Kakuta, Y.]]
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[[Category: Kakuta, Y]]
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[[Category: Kawaguchi, Y.]]
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[[Category: Kawaguchi, Y]]
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[[Category: Kimata, K.]]
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[[Category: Kimata, K]]
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[[Category: Kimura, M.]]
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[[Category: Kimura, M]]
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[[Category: Sugiura, N.]]
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[[Category: Sugiura, N]]
[[Category: Alpha/alpha troid]]
[[Category: Alpha/alpha troid]]
[[Category: Beta-sandwich]]
[[Category: Beta-sandwich]]
[[Category: Lyase activator]]
[[Category: Lyase activator]]

Revision as of 06:56, 21 December 2014

The crystal structure of novel chondroition lyase ODV-E66, baculovirus envelope protein

3vsn, resolution 2.00Å

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