1rbp

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[[Image:1rbp.gif|left|200px]]<br /><applet load="1rbp" size="350" color="white" frame="true" align="right" spinBox="true"
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[[Image:1rbp.gif|left|200px]]
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caption="1rbp, resolution 2.0&Aring;" />
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'''CRYSTALLOGRAPHIC REFINEMENT OF HUMAN SERUM RETINOL BINDING PROTEIN AT 2 ANGSTROMS RESOLUTION'''<br />
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{{Structure
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|PDB= 1rbp |SIZE=350|CAPTION= <scene name='initialview01'>1rbp</scene>, resolution 2.0&Aring;
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|SITE=
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|LIGAND= <scene name='pdbligand=RTL:RETINOL'>RTL</scene>
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|ACTIVITY=
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|GENE=
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}}
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'''CRYSTALLOGRAPHIC REFINEMENT OF HUMAN SERUM RETINOL BINDING PROTEIN AT 2 ANGSTROMS RESOLUTION'''
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==Overview==
==Overview==
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==About this Structure==
==About this Structure==
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1RBP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=RTL:'>RTL</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RBP OCA].
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1RBP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RBP OCA].
==Reference==
==Reference==
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Crystallographic refinement of human serum retinol binding protein at 2A resolution., Cowan SW, Newcomer ME, Jones TA, Proteins. 1990;8(1):44-61. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=2217163 2217163]
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Crystallographic refinement of human serum retinol binding protein at 2A resolution., Cowan SW, Newcomer ME, Jones TA, Proteins. 1990;8(1):44-61. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/2217163 2217163]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: retinol transport]]
[[Category: retinol transport]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:49:10 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:49:26 2008''

Revision as of 11:49, 20 March 2008

Image:1rbp.gif


PDB ID 1rbp

Drag the structure with the mouse to rotate
, resolution 2.0Å
Ligands:
Coordinates: save as pdb, mmCIF, xml



CRYSTALLOGRAPHIC REFINEMENT OF HUMAN SERUM RETINOL BINDING PROTEIN AT 2 ANGSTROMS RESOLUTION


Contents

Overview

Human serum retinol binding protein (RBP) in complex with retinol has been crystallographically refined to an R-factor of 18.1% with 2A resolution data. The protein topology results in an anti-parallel beta-barrel that encapsulates the retinol ligand. A detailed description of the protein and the binding site is provided. Our structural work has helped to define a family of proteins, many of which are carrier proteins for smaller ligand molecules. We describe the structural basis for the conservation of sequence within the family.

Disease

Known disease associated with this structure: Retinol binding protein, deficiency of OMIM:[180250]

About this Structure

1RBP is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Crystallographic refinement of human serum retinol binding protein at 2A resolution., Cowan SW, Newcomer ME, Jones TA, Proteins. 1990;8(1):44-61. PMID:2217163

Page seeded by OCA on Thu Mar 20 13:49:26 2008

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