Ribonuclease

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**[[4ibn]] - uRNase H - uncultured<br />
**[[4ibn]] - uRNase H - uncultured<br />
**[[4h8k]] - uRNase H + RNA + DNA<br />
**[[4h8k]] - uRNase H + RNA + DNA<br />
 +
 +
*RNase HI
 +
 +
**[[2qk9]], [[2qkb]], [[2qkk]] - hRNase HI (mutant) + RNA + DNA<br />
 +
**[[3h08]] - RNase HI - ''Chlorobaculum tepidum''<br />
 +
**[[3aa2]], [[3aa3]], [[3aa4]], [[3aa5]], [[2yv0]], [[2z1g]], [[2z1h]], [[2z1i]], [[2z1j]], [[1wse]], [[1wsf]], [[1wsg]], [[1wsh]], [[1wsi]], [[1wsj]], [[1jxb]], [[1jl1]], [[1f21]], [[1kva]], [[1kvb]], [[1kvc]], [[1goa]], [[1gob]], [[1goc]] - EcRNase HI (mutant) <br />
 +
**[[1g15]], [[1rdd]], [[1rnh]] - EcRNase HI <br />
 +
**[[1rch]] - EcRNase HI - NMR <br />
 +
**[[2zqb]] - SoRNase HI (mutant) - ''Shewanella oneidensis''<br />
 +
**[[2e4l]] - SoRNase HI <br />
 +
**[[3bsu]] - hRNase HI catalytic domain + RNA + DNA<br />
 +
**[[2ehg]] - RNase HI - ''Sulfolobus tokodaii''<br />
 +
**[[1qhk]] - yRNase HI N terminal - NMR<br />
 +
**[[3u3g]] - uRNase HI<br />
 +
**[[4e19]], [[4nyn]] - RNase HI - ''Halobacterium salinarium''<br />
 +
 +
*RNase HII
 +
 +
**[[3p83]] - AfRNase HII + DNA polymerase sliding clamp - ''Archaeoglobus fulgidus''<br />
 +
**[[1i39]], [[1i3a]] - AfRNase HII <br />
 +
**[[3puf]], [[3p56]], [[3p5j]] - hRNase HII subunits α+β+γ<br />
 +
**[[3kio]] - mRNase HII subunits α+β+γ - mouse<br />
 +
**[[3o3g]] - TmRNase HII + DNA<br />
 +
**[[3o3f]], [[3o3h]], [[4hht]] - TmRNase HII (mutant) + DNA<br />
 +
**[[2etj]] - TmRNase HII <br />
 +
**[[1x1p]], [[1io2]] - TkRNase HII - ''Thermococcus kodakarensis''<br />
 +
**[[2dfe]], [[2dff]], [[2dfh]] - TkRNase HII (mutant) <br />
 +
**[[1eke]] - RNase HII - ''Methanocaldococcus jannaschii''<br />
 +
 +
*RNase HIII
 +
 +
**[[2d0a]], [[2d0b]], [[2d0c]] - GsRNase HIII - ''Geobacillus stearothermophilus''<br />
 +
**[[3asm]] - GsRNase HIII (mutant) <br />
 +
**[[1uax]] - PhRNase HIII - ''Pyrococcus horikoshii'' <br />
 +
**[[3vn5]] - AaRNase HIII <br />
 +
 +
*RNase J
 +
 +
**[[3bk1]] - TtRNase J <br />
 +
**[[3bk2]] - TtRNase J + nucleotide<br />
 +
**[[3zq4]] - BsRNase J1 - ''Bacillus subtilis'' <br />
 +
 +
*RNase L
 +
 +
**[[4o1o]] - pRNase L + oligoadenylate + CMP - pig <br />
 +
**[[4o1p]] - pRNase L + oligoadenylate + AMPPNP <br />
 +
**[[4oav]] - pRNase L + oligoadenylate + AMPPCP + RNA<br />
 +
 +
*RNase LE
 +
 +
**[[1dix]] - RNase LE - ''Solanum lycopersicum''<br />
 +
 +
*RNase MAR1
 +
 +
**[[1xn4]] - RNase MAR1 - ''Leishmania major''<br />
 +
**[[2b34]] - RNase MAR1 - ''Caenorhabditis elegans''<br />
 +
 +
*RNase MS
 +
 +
**[[1rms]], [[1rds]] - RNase MS - ''Aspergillus phoenicis''<br />
 +
 +
*RNase MC1
 +
 +
**[[1v9h]], [[1j1f]], [[1j1g]] - McRNase MC1 (mutant) + nucleotide - ''Momordica charantia''<br />
 +
**[[1ucg]] - McRNase MC1 (mutant) <br />
 +
**[[1uca]], [[1ucc]], [[1ucd]] - McRNase MC1 + nucleotide <br />
 +
**[[1bk7]] - McRNase MC1 <br />
 +
 +
*RNase NT
 +
 +
**[[1vcz]], [[1vd1]], [[1vd3]] - NgRNase NT + nucleotide - ''Nicotiana glutinosa''<br />
 +
**[[1iyb]] - NgRNase NW <br />
 +
 +
*RNase P
 +
 +
**[[3ok7]], [[3okb]], [[3q1q]], [[3q1r]] - TmRNase P + TmRNase P RNA + tRNAPhe <br />
 +
**[[1nz0]] - TmRNase P <br />
 +
**[[1d6t]] - RNase P - ''Staphylococcus aureus''<br />
 +
**[[2a64]] - GsRNase P (mutant) <br />
 +
**[[1a6f]], [[1nbs]], [[2jg4]] - BsRNase P (mutant) <br />
 +
**[[1ts9]], [[1tsf]] - AfRNase P <br />
 +
**[[1u9s]] - RNase P - synthetic <br />
 +
**[[2avs]] - PfRNase P (mutant) - ''Pyrococcus furiosus'' <br />
 +
**[[2k3r]]. [[2ki7]] - PfRNase P <br />
 +
**[[2ljp]] - EcRNase P <br />
 +
**[[2av5]] - PhRNase P component 2<br />
 +
**[[1x0t]] - PhRNase P component 4<br />
 +
**[[2zae]] - PhRNase P components 1+4<br />
 +
**[[2czv]] - PhRNase P component 2 (mutant) +3<br />
 +
**[[3iab]] - yRNase P subunits POP6+POP7 + RNase MRP P3 domain<br />
}}
}}

Revision as of 07:54, 21 December 2014

Ribonuclease A (magenta) complex with thymidilic acid DNA tetramer (pink), 1rta

Drag the structure with the mouse to rotate

3D Structures of Ribonuclease

Updated on 21-December-2014

  • RNase I
  • 

 RNase II
  • RNase III
    • 2nue, 2nuf, 2nug, 1yyk, 1yyw, 4m2z, 4m30 - AaRNase III + RNA - Aquifex aeolicus
    • 2ez6, 1yyo, 1yz9, 1rc7 - AaRNase III (mutant) + RNA 

    • 1rc5, 1i4s, 1jfz - AaRNase III N-terminal

    • 1z5f - BuRNase III
    • 2a11 - MtRNase III - Mycobacterium tuberculosis
    • 1o0w - TmRNase III - Thermotoga maritima
      

    • 1t4n, 1t4o - yRNase III – yeast - NMR
    • 2lbs - yRNase III RNA-binding domain + RNA – NMR
    • 2lup, 4oog - yRNase III RNA-binding domain + RNA
    • 2luq - yRNase III RNA-binding domain
    • 2kb5 - hRNase 3 - NMR
      

    • 1dyt, 1qmt - hRNase 3

    • 1h1h - hRNase 3 + nucleotide
      


    • 2khx – hRNase III
    • 3n3w, 3o2r - RNase III nuclease domain – Campylobacter jejuni
  • RNase 4
    • 1wdy - hRNase 4

    • 2rnf, 1rnf - hRNase 4 + nucleotide
      

    • 1kvz - BuRNase 4 - NMR
  • RNase 5
  • RNase 6
  • RNase 7
    • 2hky - hRNase 7 - NMR
  • RNase A
  • RNase B
    • 1rbb – bRNase B
    • 1rbj - bRNase B + tetranucleotide
  • RNase BA
  • RNase D
    • 1yt3 - EcRNase D


  • RNase E
    • 2vmk, 2c4r, 2bx2 - EcRNase E catalytic domain
    • 1slj - EcRNase E S1 domain - NMR
      

    • 1smx, 1sn8 - EcRNase E S1 domain 

    • 2vrt, 2c0b - EcRNase E catalytic domain + RNA
    • 3h8a – EcRNase E recognition domain + enolase
  • RNase F1
    • 1fus, 1fut – GfRNase F1 + nucleotide – Gibberella fujikuroi
    • 1rck, 1rcl - GfRNase F1 - NMR
  • RNase H
  • RNase HI
  • RNase HII
    • 3p83 - AfRNase HII + DNA polymerase sliding clamp - Archaeoglobus fulgidus

    • 1i39, 1i3a - AfRNAse HII

    • 3puf, 3p56, 3p5j - hRNAse H2 subunits α+β+γ 

    • 3kio - mRNase H2 subunits α+β+γ 
- mouse

    • 3o3g - TmRNase HII + DNA
      

    • 3o3f, 3o3h, 4hht - TmRNase HII (mutant) + DNA
    • 2etj - TmRNase HII 

    • 1x1p, 1io2 - TkRNase HII

    • 2dfe, 2dff, 2dfh - TkRNase HII (mutant) - Thermococcus kodakarensis

    • 1eke - RNase HII - Methanocalcococcus jannaschii


  • RNase HIII
    • 2d0a, 2d0b, 2d0c - GsRNase HIII - Geobacillus stearothermophilus


    • 3asm - GsRNase HIII (mutant)
    • 1uax - PhRNase HIII – Pyrococcus horikoshii
    • 3vn5 - AaRNase HIII
  • RNase J
    • 3bk1 - TtRNase J

    • 3bk2 - TtRNase J + nucleotide
    • 3zq4 - BsRNase J1- Bacillus subtilis
  • RNase L
    • 4o1o - pRNase L + oligoadenylate + CMP – pig
    • 4o1p - pRNase L + oligoadenylate + AMPPNP
    • 4oav - hRNase L + oligoadenylate + AMPPCP + RNA
  • RNase LE
    • 1dix - RNase LE - tomato
  • RNase MAR1
    • 1xn4 - RNase MAR1 – Leishmania major
    • 2b34 - RNase MAR1 – Caenorhabditis elegans
  • RNase MS
    • 1rms, 1rds - RNase MS + nucleotide - Aspergillus phoenicis
  • RNase MC1
    • 1v9h, 1j1f, 1j1g - McRNase MC1 (mutant) + nucleotide - Momordica charantia 

    • 1ucg - McRNase MC1 (mutant)
    • 1ucd, 1uca, 1ucc - McRNase MC1 + nucleotide
    • 1bk7 - McRNase MC1


  • RNase NT
  • RNase P
    • 3ok7, 3okb, 3q1q, 3q1r - TmRNase P + TmRNase P RNA + tRNA Phe

    • 1nz0 - TmRNase P

    • 1d6t - RNase P - Staphylococcus aureus
    • 2a64 - BsRNase P (mutant) - Bacillus stearothermophilus


    • 1a6f, 1nbs, 2jg4 - BsRNase P (mutant)
    • 1ts9, 1tsf – AfRNase P
    • 1u9s – RNase P – synthetic
    • 2avs - PfRNase P (mutant) – Pyrococcus furiosus
    • 2k3r, 2ki7 - PfRNase P
    • 2ljp – EcRNase P
    • 2av5 - PhRNase P component 2
    • 1x0t - PhRNase P component 4
    • 2zae - PhRNase P component 1 and 4
    • 2czv - PhRNase P component 2 (mutant) and 3
    • 2cvz, 2zae – PhRNase P
    • 3iab – yRNase P subunits POP6 POP7 + RNase MRP P3 domain
  • RNase PH
    • 3dd6 - RNase PH - Bacillus anthracis

    • 1oyp, 1oyr, 1oys - BsRNase PH 

    • 1r6l, 1r6m - PaRNase PH - Pseudomonas aeruginosa

    • 3b4t - MtRNase PH - Mycobacterium tuberculosis 

    • 1udn - AaRNase PH

    • 1udo, 1udq, 1uds - AaRNase PH (mutant)


  • RNase RH
    • 1bol – Rhizopus niveus
  • RNase S
  • RNase S3
    • 1iqq - RNase S3 - Japanese pear
  • RNase SA
  • RNase SA2
  • RNase SA3
  • RNase SF11
    • 1ioo - RNase SF11 - Nicotiana alata


  • RNase T
  • RNase T1
  • RNase T2
  • RNase U2
    • 3agn, 3ago, 3ahw - UsRNase U2 + AMP - Ustilago sphaerogena

    • 1rtu - UsRNase U2
  • RNase U2B
  • RNase Z
  • α-sarcin
    • 1de3 - αsRNase – Aspergillus giganteus
    • 1r4y - αsRNase (mutant)
  • Oligoribonuclease
    • 2igi, 1yta – EcORNase
    • 2gbz - ORNase - Xanthomonas campestris
    • 1j9a - ORNase - Haemophilus influenzae
    • 3tr8 – ORNase – Coxiella burnetii
  • Polynucleotide Phosphorylase
    • 3cdi - EcPNPase
    • 3gll - EcPNPase core
    • 3cdj - EcPNPase C-terminal truncated
    • 1e3h, 1e3p - PNPase - Streptomyces antibioticus
    • 3gcm, 3gme, 3h1c - EcPNPase + RNase E recognition domain
    • 3h36 - PNPase fragment - Streptococcus mutans
  • Binase
  • Poly(A)-specific RNase
    • 1ug8 – mParn R3H domain - NMR
    • 1whv – mParn RNA-binding domain - NMR
    • 2rok - mParn CAP-binding domain - NMR
    • 3d45 - mParn + nucleotide
    • 2a1s - hParn
    • 2a1r, 3ctr – hParn + nucleotide
    • 2zpo – RNase – Chelonia mydas
    • 3a4y, 3idz, 3ie0, 3ie2 – TtRNase (mutant) – Thermus thermophilus
    • 3iek - TtRNase
    • 3ie1, 3iem - TtRNase (mutant) + RNA
    • 3iel - TtRNase + nucleotide
    • 4b8a – yRNase pop2 + cell division cycle protein 39
    • 4b8c – yRNase pop2 + cell division cycle protein 39 + CCR4

}}

References

  1. ↑ Birdsall DL, McPherson A. Crystal structure disposition of thymidylic acid tetramer in complex with ribonuclease A. J Biol Chem. 1992 Nov 5;267(31):22230-6. PMID:1429575
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