Ribonuclease

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**[[3iab]] - yRNase P subunits POP6+POP7 + RNase MRP P3 domain<br />
**[[3iab]] - yRNase P subunits POP6+POP7 + RNase MRP P3 domain<br />
 +
*RNase PH
 +
 +
**[[3dd6]] - RNase PH - ''Bacillus anthracis'' <br />
 +
**[[1oyp]], [[1oyr]], [[1oys]] - BsRNase PH <br />
 +
**[[1r6l]], [[1r6m]] - PaRNase PH - ''Pseudomonas aeruginosa''<br />
 +
**[[3b4t]] - MtRNase PH <br />
 +
**[[1udn]] - AaRNase PH <br />
 +
**[[1udo]], [[1udq]], [[1uds]] - AaRNase PH (mutant)<br />
 +
 +
*RNase RH
 +
 +
**[[1bol]] - RNase RH - ''Rhizopus niveus'' <br />
 +
 +
*RNase S
 +
 +
**[[3oqy]], [[3oqz]], [[3or0]], [[1z3l]], [[1z3m]], [[1z3p]], [[1y92]], [[1y94]], [[1fev]], [[1d5d]], [[1d5e]], [[1d5h]], [[2rln]], [[1qwq]], [[4n4c]] - bRNase S seminal (mutant) <br />
 +
**[[1tq9]], [[1r5c]], [[11ba]], [[11bg]] - bRNase S + nucleotide <br />
 +
**[[1r5d]], [[1r3m]], [[1n1x]], [[1n3z]], [[1j7z]], [[1j80]], [[1j81]], [[1j82]], [[1cjq]], [[1cjr]], [[1bsr]], [[1rbc]], [[1rbd]], [[1rbe]], [[1rbf]], [[1rbg]], [[1rbh]] [[1rbi]], [[1rnu]], [[1rnv]], [[2rns]] - bRNase S <br />
 +
**[[1b6v]] - bRNase S/bRNase A <br />
 +
 +
*RNase S3
 +
 +
**[[1iqq]] - RNase S3 - Japanese pear <br />
 +
 +
*RNase SA
 +
 +
**[[3a5e]], [[1zgx]], [[1ynv]], [[1t2h]], [[1t2i]], [[1uci]], [[1ucj]], [[1uck]], [[1ucl]], [[1i70]], [[1i8v]], [[1box]], [[4gho]] - SaRNase SA guanyl-specific (mutant) - ''Streptomyces aureofaciens'' <br />
 +
**[[1lni]], [[1c54]], [[1rge]], [[1rgf]], [[1rgg]], [[1rgh]], [[1sar]] - SaRNase SA <br />
 +
**[[1gmp]], [[1gmq]], [[1gmr]], [[2sar]] - SaRNase SA + nucleotide <br />
 +
**[[1ay7]] - SaRNase SA + barstar <br />
 +
**[[1rsn]] - SaRNase SA + cyclophosphothiolate <br />
 +
**[[1py3]], [[1pyl]] - SaRNase SA2 <br />
 +
**[[3dgy]], [[3dh2]], [[3d4a]], [[3d5g]], [[3d5i]] - SaRNase SA2 + nucleotide <br />
 +
**[[1mgr]], [[1mgw]] - SaRNase SA3 <br />
 +
 +
*RNase SF11
 +
 +
**[[1ioo]] - RNase SF11 - ''Nicotiana alata'' <br />
 +
 +
*RNase T
 +
 +
**[[2is3]] - EcRNase T <br />
 +
**[[3ngy]] - EcRNase T (mutant)<br />
 +
**[[3ngz]] - EcRNase T (mutant) + nucleotide<br />
 +
**[[3ngo]], [[3nh1]], [[3nh2]] - EcRNase T + nucleotide<br />
 +
**[[3v9s]], [[3v9w]], [[3v9u]], [[3v9x]], [[3v9z]], [[3va0]], [[3va3]], [[4kaz]], [[4kb0]], [[4kb1]] - EcRNase T + DNA<br />
 +
**[[2f96]] - PaRNase T <br />
 +
 +
*RNase T1
 +
 +
**[[1tto]], [[1rn1]], [[1rn4]], [[1rnt]], [[2aad]], [[2aae]] - AoRNase T1 - ''Aspergillus oryzae'' <br />
 +
**[[1q9e]], [[1iyy]], [[1i2e]], [[1i2f]], [[1i2g]], [[1i3f]], [[1i3i]], [[1hz1]], [[1fys]], [[1fzu]], [[1ch0]], [[4bir]], [[3bir]], [[5bir]], [[1g02]], [[1hyf]], [[1trp]], [[1trq]], [[2bir]], [[4rnt]], [[5rnt]], [[6rnt]], [[7rnt]], [[8rnt]], [[9rnt]] - AoRNase T1 (mutant)<br />
 +
**[[1lov]], [[1low]], [[1loy]], [[1i0v]], [[1i0x]], [[1b2m]], [[1rhl]], [[1bir]], [[1rgk]], [[1rgl]] - AoRNase T1 (mutant) + nucleotide<br />
 +
**[[1bvi]], [[2bu4]], [[2hoh]], [[3hoh]], [[4hoh]], [[5hoh]], [[1gsp]], [[2gsp]]. [[3gsp]], [[4gsp]], [[5gsp]]. [[6gsp]], [[7gsp]], [[1det]], [[1rls]], [[1lra]], [[1rga]], [[1bu4]], [[1rgc]], [[3bu4]], [[4bu4]], [[5bu4]], [[3syu]], [[3urp]] - AoRNase T1 + nucleotide<br />
 +
**[[3rnt]] - AoRNase T1 + V<br />
 +
**[[1ygw]] - AoRNase T1 - NMR<br />
 +
 +
*RNase T2
 +
 +
**[[3t0o]] - hRNase T2<br />
 +
 +
*RNase U2
 +
 +
**[[3agn]], [[3ago]], [[3ahw]] - UsRNase U2 + AMP - ''Ustilago sphaerogena''<br />
 +
**[[1rtu]] - UsRNase U2<br />
 +
**[[3ahs]] - UsRNase U2B<br />
 +
 +
*RNase Z
 +
 +
**[[2e7y]] - TmRNase Z<br />
 +
**[[2fk6]], [[4gcw]] - BsRNase Z (mutant) + tRNA Thr<br />
 +
**[[1y44]] - BsRNase Z (mutant) <br />
 +
**[[2cbn]] - EcRNase Z<br />
 +
**[[3v32]], [[3v33]], [[3v34]] - hRNase Z<br />
 +
 +
*RNase α-sarcin
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**[[1de3]] - AgRNase αs - ''Aspergillus giganteus''<br />
 +
**[[1r4y]] - AgRNase αs (mutant)<br />
 +
 +
*Oligoribonuclease
 +
 +
**[[2igi]], [[1yta]] - EcORNase<br />
 +
**[[2gbz]] - ORNase - ''Xanthomonas campestris''<br />
 +
**[[1j9a]] - ORNase - ''Haemophilus influenza''<br />
 +
**[[3tr8]] - ORNase - ''Coxiella burnetii''<br />
 +
 +
*Polynucleotide phosphorylase
 +
 +
**[[3cdi]] - EcPNPase<br />
 +
**[[3gll]] - EcPNPase core<br />
 +
**[[3cdj]] - EcPNPase C terminal truncated<br />
 +
**[[1e3h]], [[1e3p]] - PNPase - ''Streptomyces antibioticus''<br />
 +
**[[3gcm]], [[3gme]], [[3h1c]] - EcPNPase + RNase E recognition domain<br />
 +
**[[3h36]] - PNPase fragment - ''Streptomyces mutans''<br />
 +
 +
*Binase
 +
 +
**[[1gou]], [[1gov]], [[1goy]] - BiBinase - ''Bacillus intermedius''<br />
 +
**[[2rbi]], [[4haa]] - BiBinase (mutant)<br />
 +
**[[1buj]] - BiBinase - NMR<br />
 +
 +
*Poly(A)-specific RNase
 +
 +
**[[1ug8]] - mParn R3H domain - NMR<br />
 +
**[[1whv]] - mParn RNA-binding domain - NMR<br />
 +
**[[2rok]] - mParn CAP-binding domain - NMR<br />
 +
**[[3d45]] - mParn + nucleotide<br />
 +
**[[2a1s]] - hParn <br />
 +
**[[2a1r]], [[3ctr]] - hParn + nucleotide<br />
 +
 +
*RNase pop2
 +
 +
**[[4b8a]] - yRNase pop2 + cell division cycle protein 39<br />
 +
**[[4b8c]] - yRNase pop2 + cell division cycle protein 39 + CCR4<br />
 +
 +
*Other RNases
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 +
**[[2zpo]] - RNase - ''Chelonia mydas''<br />
 +
**[[3a4y]], [[3idz]], [[3ie0]], [[3ie2]] - TtRNase (mutant) - ''Thermus thermophilus''<br />
 +
**[[3iek]] - TtRNase<br />
 +
**[[3ie1]], [[3iem]] - TtRNase (mutant)<br />
 +
**[[3iel]] - TtRNase + nucleotide<br />
}}
}}

Revision as of 07:55, 21 December 2014

Ribonuclease A (magenta) complex with thymidilic acid DNA tetramer (pink), 1rta

Drag the structure with the mouse to rotate

3D Structures of Ribonuclease

Updated on 21-December-2014

  • RNase I
  • 

 RNase II
  • RNase III
    • 2nue, 2nuf, 2nug, 1yyk, 1yyw, 4m2z, 4m30 - AaRNase III + RNA - Aquifex aeolicus
    • 2ez6, 1yyo, 1yz9, 1rc7 - AaRNase III (mutant) + RNA 

    • 1rc5, 1i4s, 1jfz - AaRNase III N-terminal

    • 1z5f - BuRNase III
    • 2a11 - MtRNase III - Mycobacterium tuberculosis
    • 1o0w - TmRNase III - Thermotoga maritima
      

    • 1t4n, 1t4o - yRNase III – yeast - NMR
    • 2lbs - yRNase III RNA-binding domain + RNA – NMR
    • 2lup, 4oog - yRNase III RNA-binding domain + RNA
    • 2luq - yRNase III RNA-binding domain
    • 2kb5 - hRNase 3 - NMR
      

    • 1dyt, 1qmt - hRNase 3

    • 1h1h - hRNase 3 + nucleotide
      


    • 2khx – hRNase III
    • 3n3w, 3o2r - RNase III nuclease domain – Campylobacter jejuni
  • RNase 4
    • 1wdy - hRNase 4

    • 2rnf, 1rnf - hRNase 4 + nucleotide
      

    • 1kvz - BuRNase 4 - NMR
  • RNase 5
  • RNase 6
  • RNase 7
    • 2hky - hRNase 7 - NMR
  • RNase A
  • RNase B
    • 1rbb – bRNase B
    • 1rbj - bRNase B + tetranucleotide
  • RNase BA
  • RNase D
    • 1yt3 - EcRNase D


  • RNase E
    • 2vmk, 2c4r, 2bx2 - EcRNase E catalytic domain
    • 1slj - EcRNase E S1 domain - NMR
      

    • 1smx, 1sn8 - EcRNase E S1 domain 

    • 2vrt, 2c0b - EcRNase E catalytic domain + RNA
    • 3h8a – EcRNase E recognition domain + enolase
  • RNase F1
    • 1fus, 1fut – GfRNase F1 + nucleotide – Gibberella fujikuroi
    • 1rck, 1rcl - GfRNase F1 - NMR
  • RNase H
  • RNase HI
  • RNase HII
    • 3p83 - AfRNase HII + DNA polymerase sliding clamp - Archaeoglobus fulgidus

    • 1i39, 1i3a - AfRNAse HII

    • 3puf, 3p56, 3p5j - hRNAse H2 subunits α+β+γ 

    • 3kio - mRNase H2 subunits α+β+γ 
- mouse

    • 3o3g - TmRNase HII + DNA
      

    • 3o3f, 3o3h, 4hht - TmRNase HII (mutant) + DNA
    • 2etj - TmRNase HII 

    • 1x1p, 1io2 - TkRNase HII

    • 2dfe, 2dff, 2dfh - TkRNase HII (mutant) - Thermococcus kodakarensis

    • 1eke - RNase HII - Methanocalcococcus jannaschii


  • RNase HIII
    • 2d0a, 2d0b, 2d0c - GsRNase HIII - Geobacillus stearothermophilus


    • 3asm - GsRNase HIII (mutant)
    • 1uax - PhRNase HIII – Pyrococcus horikoshii
    • 3vn5 - AaRNase HIII
  • RNase J
    • 3bk1 - TtRNase J

    • 3bk2 - TtRNase J + nucleotide
    • 3zq4 - BsRNase J1- Bacillus subtilis
  • RNase L
    • 4o1o - pRNase L + oligoadenylate + CMP – pig
    • 4o1p - pRNase L + oligoadenylate + AMPPNP
    • 4oav - hRNase L + oligoadenylate + AMPPCP + RNA
  • RNase LE
    • 1dix - RNase LE - tomato
  • RNase MAR1
    • 1xn4 - RNase MAR1 – Leishmania major
    • 2b34 - RNase MAR1 – Caenorhabditis elegans
  • RNase MS
    • 1rms, 1rds - RNase MS + nucleotide - Aspergillus phoenicis
  • RNase MC1
    • 1v9h, 1j1f, 1j1g - McRNase MC1 (mutant) + nucleotide - Momordica charantia 

    • 1ucg - McRNase MC1 (mutant)
    • 1ucd, 1uca, 1ucc - McRNase MC1 + nucleotide
    • 1bk7 - McRNase MC1


  • RNase NT
  • RNase P
    • 3ok7, 3okb, 3q1q, 3q1r - TmRNase P + TmRNase P RNA + tRNA Phe

    • 1nz0 - TmRNase P

    • 1d6t - RNase P - Staphylococcus aureus
    • 2a64 - BsRNase P (mutant) - Bacillus stearothermophilus


    • 1a6f, 1nbs, 2jg4 - BsRNase P (mutant)
    • 1ts9, 1tsf – AfRNase P
    • 1u9s – RNase P – synthetic
    • 2avs - PfRNase P (mutant) – Pyrococcus furiosus
    • 2k3r, 2ki7 - PfRNase P
    • 2ljp – EcRNase P
    • 2av5 - PhRNase P component 2
    • 1x0t - PhRNase P component 4
    • 2zae - PhRNase P component 1 and 4
    • 2czv - PhRNase P component 2 (mutant) and 3
    • 2cvz, 2zae – PhRNase P
    • 3iab – yRNase P subunits POP6 POP7 + RNase MRP P3 domain
  • RNase PH
    • 3dd6 - RNase PH - Bacillus anthracis

    • 1oyp, 1oyr, 1oys - BsRNase PH 

    • 1r6l, 1r6m - PaRNase PH - Pseudomonas aeruginosa

    • 3b4t - MtRNase PH - Mycobacterium tuberculosis 

    • 1udn - AaRNase PH

    • 1udo, 1udq, 1uds - AaRNase PH (mutant)


  • RNase RH
    • 1bol – Rhizopus niveus
  • RNase S
  • RNase S3
    • 1iqq - RNase S3 - Japanese pear
  • RNase SA
  • RNase SA2
  • RNase SA3
  • RNase SF11
    • 1ioo - RNase SF11 - Nicotiana alata


  • RNase T
  • RNase T1
  • RNase T2
  • RNase U2
    • 3agn, 3ago, 3ahw - UsRNase U2 + AMP - Ustilago sphaerogena

    • 1rtu - UsRNase U2
  • RNase U2B
  • RNase Z
  • α-sarcin
    • 1de3 - αsRNase – Aspergillus giganteus
    • 1r4y - αsRNase (mutant)
  • Oligoribonuclease
    • 2igi, 1yta – EcORNase
    • 2gbz - ORNase - Xanthomonas campestris
    • 1j9a - ORNase - Haemophilus influenzae
    • 3tr8 – ORNase – Coxiella burnetii
  • Polynucleotide Phosphorylase
    • 3cdi - EcPNPase
    • 3gll - EcPNPase core
    • 3cdj - EcPNPase C-terminal truncated
    • 1e3h, 1e3p - PNPase - Streptomyces antibioticus
    • 3gcm, 3gme, 3h1c - EcPNPase + RNase E recognition domain
    • 3h36 - PNPase fragment - Streptococcus mutans
  • Binase
  • Poly(A)-specific RNase
    • 1ug8 – mParn R3H domain - NMR
    • 1whv – mParn RNA-binding domain - NMR
    • 2rok - mParn CAP-binding domain - NMR
    • 3d45 - mParn + nucleotide
    • 2a1s - hParn
    • 2a1r, 3ctr – hParn + nucleotide
    • 2zpo – RNase – Chelonia mydas
    • 3a4y, 3idz, 3ie0, 3ie2 – TtRNase (mutant) – Thermus thermophilus
    • 3iek - TtRNase
    • 3ie1, 3iem - TtRNase (mutant) + RNA
    • 3iel - TtRNase + nucleotide
    • 4b8a – yRNase pop2 + cell division cycle protein 39
    • 4b8c – yRNase pop2 + cell division cycle protein 39 + CCR4

}}

References

  1. ↑ Birdsall DL, McPherson A. Crystal structure disposition of thymidylic acid tetramer in complex with ribonuclease A. J Biol Chem. 1992 Nov 5;267(31):22230-6. PMID:1429575
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