3zpg
From Proteopedia
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| - | + | ==Acinetobacter baumannii RibD, form 2== | |
| - | ===Acinetobacter baumannii | + | <StructureSection load='3zpg' size='340' side='right' caption='[[3zpg]], [[Resolution|resolution]] 1.99Å' scene=''> |
| - | + | == Structural highlights == | |
| + | <table><tr><td colspan='2'>[[3zpg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Acinetobacter_baumannii Acinetobacter baumannii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZPG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZPG FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5GP:GUANOSINE-5-MONOPHOSPHATE'>5GP</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=OXL:OXALATE+ION'>OXL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3zpc|3zpc]]</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zpg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zpg RCSB], [http://www.ebi.ac.uk/pdbsum/3zpg PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase (RibD) represents a potential antibacterial drug target. The structure of recombinant Acinetobacter baumannii RibD is reported in orthorhombic and tetragonal crystal forms at 2.2 and 2.0 A resolution, respectively. Comparisons with orthologous structures in the Protein Data Bank indicated close similarities. The tetragonal crystal form was obtained in the presence of guanosine monophosphate, which surprisingly was observed to occupy the adenine-binding site of the reductase domain. | ||
| - | + | Structure of diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase from Acinetobacter baumannii.,Dawson A, Trumper P, Chrysostomou G, Hunter WN Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Jun;69(Pt 6):611-7. doi:, 10.1107/S174430911301292X. Epub 2013 May 23. PMID:23722836<ref>PMID:23722836</ref> | |
| - | + | ||
| - | == | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
| - | + | </div> | |
| + | |||
| + | ==See Also== | ||
| + | *[[Carbonic anhydrase|Carbonic anhydrase]] | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Acinetobacter baumannii]] | [[Category: Acinetobacter baumannii]] | ||
| - | [[Category: Chrysostomou, G | + | [[Category: Chrysostomou, G]] |
| - | [[Category: Dawson, A | + | [[Category: Dawson, A]] |
| - | [[Category: Hunter, W N | + | [[Category: Hunter, W N]] |
| - | [[Category: Trumper, P | + | [[Category: Trumper, P]] |
[[Category: Deaminase]] | [[Category: Deaminase]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Reductase]] | [[Category: Reductase]] | ||
Revision as of 08:49, 21 December 2014
Acinetobacter baumannii RibD, form 2
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