401d
From Proteopedia
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| - | + | ==STRUCTURE OF A DNA IN LOW SALT CONDITIONS D(GACCGCGGTC)== | |
| - | + | <StructureSection load='401d' size='340' side='right' caption='[[401d]], [[Resolution|resolution]] 2.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| + | <table><tr><td colspan='2'>[[401d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=401D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=401D FirstGlance]. <br> | ||
| + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=401d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=401d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=401d RCSB], [http://www.ebi.ac.uk/pdbsum/401d PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The X-ray crystal structure of the DNA decamer d(GACCGCGGTC), containing half the human papilloma virus E2 binding site, has been solved from two crystals grown at different ionic conditions (50 mM MgCl2and 50 mM spermine or 1.56 mM MgCl2and 1.56 mM spermine). Despite the variation in salt concentration, the two DNA structures are in a very similar, A-type DNA conformation, with helical axes curving towards the major groove. Although the salt concentrations do not effect the helical parameters or hydration to a large degree, there is a change in the overall helical curvature; 18 degrees and 31 degrees for the low and high salt structures, respectively. This curvature appears to be sequence specific and biologically relevant when compared with similar DNA structures, including the E2 binding site of a protein-DNA complex. | ||
| - | + | X-ray crystal structures of half the human papilloma virus E2 binding site: d(GACCGCGGTC).,Finley JB, Luo M Nucleic Acids Res. 1998 Dec 15;26(24):5719-27. PMID:9838004<ref>PMID:9838004</ref> | |
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| - | == | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
| - | + | </div> | |
| - | [[Category: Finley, J B | + | == References == |
| - | [[Category: Luo, M | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Finley, J B]] | ||
| + | [[Category: Luo, M]] | ||
[[Category: Dna]] | [[Category: Dna]] | ||
[[Category: Dna double helix]] | [[Category: Dna double helix]] | ||
Revision as of 09:00, 21 December 2014
STRUCTURE OF A DNA IN LOW SALT CONDITIONS D(GACCGCGGTC)
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