1rhw
From Proteopedia
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| - | [[Image:1rhw.jpg|left|200px]] | + | [[Image:1rhw.jpg|left|200px]] |
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| - | '''The solution structure of the pH-induced monomer of dynein light chain LC8 from Drosophila''' | + | {{Structure |
| + | |PDB= 1rhw |SIZE=350|CAPTION= <scene name='initialview01'>1rhw</scene> | ||
| + | |SITE= | ||
| + | |LIGAND= | ||
| + | |ACTIVITY= | ||
| + | |GENE= CTP, CDLC1, DDLC1, CG6998 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 Drosophila melanogaster]) | ||
| + | }} | ||
| + | |||
| + | '''The solution structure of the pH-induced monomer of dynein light chain LC8 from Drosophila''' | ||
| + | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1RHW is a [ | + | 1RHW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RHW OCA]. |
==Reference== | ==Reference== | ||
| - | The solution structure of the pH-induced monomer of dynein light-chain LC8 from Drosophila., Makokha M, Huang YJ, Montelione G, Edison AS, Barbar E, Protein Sci. 2004 Mar;13(3):727-34. Epub 2004 Feb 6. PMID:[http:// | + | The solution structure of the pH-induced monomer of dynein light-chain LC8 from Drosophila., Makokha M, Huang YJ, Montelione G, Edison AS, Barbar E, Protein Sci. 2004 Mar;13(3):727-34. Epub 2004 Feb 6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14767079 14767079] |
[[Category: Drosophila melanogaster]] | [[Category: Drosophila melanogaster]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: domain swapped]] | [[Category: domain swapped]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:51:53 2008'' |
Revision as of 11:51, 20 March 2008
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| Gene: | CTP, CDLC1, DDLC1, CG6998 (Drosophila melanogaster) | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
The solution structure of the pH-induced monomer of dynein light chain LC8 from Drosophila
Overview
The structure of Drosophila LC8 pH-induced monomer has been determined by NMR spectroscopy using the program AutoStructure. The structure at pH 3 and 30 degrees C is similar to the individual subunits of mammalian LC8 dimer with the exception that a beta strand, which crosses between monomers to form an intersubunit beta-sheet in the dimer, is a flexible loop with turnlike conformations in the monomer. Increased flexibility in the interface region relative to the rest of the protein is confirmed by dynamic measurements based on (15)N relaxation. Comparison of the monomer and dimer structures indicates that LC8 is not a domain swapped dimer.
About this Structure
1RHW is a Single protein structure of sequence from Drosophila melanogaster. Full crystallographic information is available from OCA.
Reference
The solution structure of the pH-induced monomer of dynein light-chain LC8 from Drosophila., Makokha M, Huang YJ, Montelione G, Edison AS, Barbar E, Protein Sci. 2004 Mar;13(3):727-34. Epub 2004 Feb 6. PMID:14767079
Page seeded by OCA on Thu Mar 20 13:51:53 2008
