3wgv

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{{STRUCTURE_3wgv| PDB=3wgv | SCENE= }}
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==Crystal structure of a Na+-bound Na+,K+-ATPase preceding the E1P state with oligomycin==
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===Crystal structure of a Na+-bound Na+,K+-ATPase preceding the E1P state with oligomycin===
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<StructureSection load='3wgv' size='340' side='right' caption='[[3wgv]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[3wgv]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WGV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WGV FirstGlance]. <br>
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[[http://www.uniprot.org/uniprot/AT1B1_PIG AT1B1_PIG]] This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ALF:TETRAFLUOROALUMINATE+ION'>ALF</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=EFO:OLIGOMYCIN+A'>EFO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PC1:1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PC1</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2zxe|2zxe]], [[2zbd|2zbd]], [[3wgu|3wgu]]</td></tr>
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==About this Structure==
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Sodium/potassium-exchanging_ATPase Sodium/potassium-exchanging ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.9 3.6.3.9] </span></td></tr>
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[[3wgv]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WGV OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wgv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wgv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wgv RCSB], [http://www.ebi.ac.uk/pdbsum/3wgv PDBsum]</span></td></tr>
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</table>
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__TOC__
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</StructureSection>
[[Category: Sodium/potassium-exchanging ATPase]]
[[Category: Sodium/potassium-exchanging ATPase]]
[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
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[[Category: Cornelius, F.]]
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[[Category: Cornelius, F]]
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[[Category: Kanai, R.]]
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[[Category: Kanai, R]]
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[[Category: Ogawa, H.]]
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[[Category: Ogawa, H]]
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[[Category: Toyoshima, C.]]
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[[Category: Toyoshima, C]]
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[[Category: Vilsen, B.]]
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[[Category: Vilsen, B]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Atpase]]
[[Category: Atpase]]

Revision as of 09:07, 21 December 2014

Crystal structure of a Na+-bound Na+,K+-ATPase preceding the E1P state with oligomycin

3wgv, resolution 2.80Å

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