4au5

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{{STRUCTURE_4au5| PDB=4au5 | SCENE= }}
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==Structure of the NhaA dimer, crystallised at low pH==
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===Structure of the NhaA dimer, crystallised at low pH===
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<StructureSection load='4au5' size='340' side='right' caption='[[4au5]], [[Resolution|resolution]] 3.70&Aring;' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[4au5]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AU5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AU5 FirstGlance]. <br>
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[[http://www.uniprot.org/uniprot/NHAA_ECOLI NHAA_ECOLI]] Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. Catalyzes the exchange of 2 H(+) per Na(+). Can mediate sodium uptake when a transmembrane pH gradient is applied. Active at alkaline pH. Activity is strongly down-regulated below pH 6.5.<ref>PMID:1645730</ref>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LMU:DODECYL-ALPHA-D-MALTOSIDE'>LMU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1zcd|1zcd]], [[4atv|4atv]]</td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4au5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4au5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4au5 RCSB], [http://www.ebi.ac.uk/pdbsum/4au5 PDBsum]</span></td></tr>
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[[4au5]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AU5 OCA].
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</table>
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__TOC__
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==Reference==
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</StructureSection>
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<references group="xtra"/><references/>
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Cameron, A D.]]
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[[Category: Cameron, A D]]
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[[Category: Drew, D.]]
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[[Category: Drew, D]]
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[[Category: Iwata, S.]]
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[[Category: Iwata, S]]
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[[Category: Lee, C.]]
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[[Category: Lee, C]]
[[Category: Membrane protein]]
[[Category: Membrane protein]]
[[Category: Transporter]]
[[Category: Transporter]]

Revision as of 09:41, 21 December 2014

Structure of the NhaA dimer, crystallised at low pH

4au5, resolution 3.70Å

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