4gca

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{{STRUCTURE_4gca| PDB=4gca | SCENE= }}
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==Complex of Aldose Reductase with inhibitor IDD 1219==
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===Complex of Aldose Reductase with inhibitor IDD 1219===
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<StructureSection load='4gca' size='340' side='right' caption='[[4gca]], [[Resolution|resolution]] 0.90&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4gca]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GCA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GCA FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2X9:{2,6-DIMETHYL-5-[(4,5,7-TRIFLUORO-1,3-BENZOTHIAZOL-2-YL)METHYL]PYRIDIN-3-YL}ACETIC+ACID'>2X9</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1us0|1us0]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AKR1B1, ALDR1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gca FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gca OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gca RCSB], [http://www.ebi.ac.uk/pdbsum/4gca PDBsum]</span></td></tr>
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</table>
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==Function==
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==See Also==
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[[http://www.uniprot.org/uniprot/ALDR_HUMAN ALDR_HUMAN]] Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
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*[[Aldose Reductase|Aldose Reductase]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[4gca]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GCA OCA].
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[[Category: Aldehyde reductase]]
[[Category: Aldehyde reductase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Geraci, L S.]]
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[[Category: Geraci, L S]]
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[[Category: Podjarny, A D.]]
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[[Category: Podjarny, A D]]
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[[Category: Zandt, M Van.]]
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[[Category: Zandt, M Van]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
[[Category: Tim barrel]]
[[Category: Tim barrel]]

Revision as of 10:39, 21 December 2014

Complex of Aldose Reductase with inhibitor IDD 1219

4gca, resolution 0.90Å

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