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4gfv

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{{STRUCTURE_4gfv| PDB=4gfv | SCENE= }}
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==PTPN18 in complex with HER2-pY1196 phosphor-peptides==
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===PTPN18 in complex with HER2-pY1196 phosphor-peptides===
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<StructureSection load='4gfv' size='340' side='right' caption='[[4gfv]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4gfv]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GFV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GFV FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4gfu|4gfu]], [[4gfw|4gfw]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PTPN18, BDP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gfv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gfv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gfv RCSB], [http://www.ebi.ac.uk/pdbsum/4gfv PDBsum]</span></td></tr>
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</table>
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==Function==
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==See Also==
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[[http://www.uniprot.org/uniprot/PTN18_HUMAN PTN18_HUMAN]] Differentially dephosphorylate autophosphorylated tyrosine kinases which are known to be overexpressed in tumor tissues.
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*[[Tyrosine phosphatase|Tyrosine phosphatase]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[4gfv]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GFV OCA].
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein-tyrosine-phosphatase]]
[[Category: Protein-tyrosine-phosphatase]]
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[[Category: Du, Y J.]]
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[[Category: Du, Y J]]
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[[Category: Sun, J P.]]
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[[Category: Sun, J P]]
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[[Category: Wang, H M.]]
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[[Category: Wang, H M]]
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[[Category: Yang, D X.]]
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[[Category: Yang, D X]]
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[[Category: Yang, F.]]
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[[Category: Yang, F]]
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[[Category: Yu, X.]]
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[[Category: Yu, X]]
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[[Category: Zhang, Y.]]
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[[Category: Zhang, Y]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Hydrolase-peptide complex]]
[[Category: Hydrolase-peptide complex]]
[[Category: Phosphatase]]
[[Category: Phosphatase]]
[[Category: Tyrosine phosphorylation]]
[[Category: Tyrosine phosphorylation]]

Revision as of 10:47, 21 December 2014

PTPN18 in complex with HER2-pY1196 phosphor-peptides

4gfv, resolution 2.10Å

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