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4f44

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{{STRUCTURE_4f44| PDB=4f44 | SCENE= }}
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==Neurotrophin p75NTR intracellular domain==
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===Neurotrophin p75NTR intracellular domain===
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<StructureSection load='4f44' size='340' side='right' caption='[[4f44]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[4f44]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F44 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4F44 FirstGlance]. <br>
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[[http://www.uniprot.org/uniprot/TNR16_RAT TNR16_RAT]] Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells.
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MNB:5-MERCAPTO-2-NITRO-BENZOIC+ACID'>MNB</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4f42|4f42]]</td></tr>
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==About this Structure==
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Ngfr, NM_012610, Tnfrsf16 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr>
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[[4f44]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F44 OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4f44 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f44 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4f44 RCSB], [http://www.ebi.ac.uk/pdbsum/4f44 PDBsum]</span></td></tr>
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</table>
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__TOC__
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</StructureSection>
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Jiang, T.]]
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[[Category: Jiang, T]]
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[[Category: Qu, Q.]]
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[[Category: Qu, Q]]
[[Category: Death domain]]
[[Category: Death domain]]
[[Category: Signaling protein]]
[[Category: Signaling protein]]
[[Category: Signaling tranduction]]
[[Category: Signaling tranduction]]

Revision as of 10:53, 21 December 2014

Neurotrophin p75NTR intracellular domain

4f44, resolution 2.40Å

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