4fzs

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-	{{STRUCTURE_4fzs| PDB=4fzs | SCENE= }}	+	==Structure of human SNX1 BAR domain==
-	===Structure of human SNX1 BAR domain===	+	<StructureSection load='4fzs' size='340' side='right' caption='[[4fzs]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4fzs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FZS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FZS FirstGlance]. <br>
		+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SNX1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fzs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fzs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4fzs RCSB], [http://www.ebi.ac.uk/pdbsum/4fzs PDBsum]</span></td></tr>
		+	</table>
-	==Function==	+	==See Also==
-	[[http://www.uniprot.org/uniprot/SNX1_HUMAN SNX1_HUMAN]] May be involved in several stages of intracellular trafficking. Plays a role in targeting ligand-activated EGFR to the lysosomes for degradation after endocytosis from the cell surface and release from the Golgi. Component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).<ref>PMID:12198132</ref> <ref>PMID:15498486</ref> <ref>PMID:17101778</ref>	+	*[[Sorting nexin|Sorting nexin]]
-		+	__TOC__
-	==About this Structure==	+	</StructureSection>
-	[[4fzs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FZS OCA].	+
-		+
-	==Reference==	+
-	<references group="xtra"/><references/>	+
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Bhatia, V K.]]	+	[[Category: Bhatia, V K]]
-	[[Category: Cullen, P J.]]	+	[[Category: Cullen, P J]]
-	[[Category: Hurley, J H.]]	+	[[Category: Hurley, J H]]
-	[[Category: Kloer, D P.]]	+	[[Category: Kloer, D P]]
-	[[Category: Sessions, R B.]]	+	[[Category: Sessions, R B]]
-	[[Category: Stamou, D.]]	+	[[Category: Stamou, D]]
-	[[Category: Traer, C J.]]	+	[[Category: Traer, C J]]
-	[[Category: Weering, J R.T van.]]	+	[[Category: Weering, J R.T van]]
	[[Category: Bar]]		[[Category: Bar]]
	[[Category: Membrane remodeling]]		[[Category: Membrane remodeling]]
	[[Category: Protein transport]]		[[Category: Protein transport]]

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Revision as of 10:53, 21 December 2014

Structure of human SNX1 BAR domain

spinqualitylabelsall models 4fzs, resolution 2.80Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Structural highlights 4fzs is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Gene: SNX1 (Homo sapiens) Resources: FirstGlance, OCA, RCSB, PDBsum See Also Sorting nexin Contents 1 Structural highlights 2 See Also