4ein
From Proteopedia
(Difference between revisions)
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| - | + | ==Crystal structure of mouse thymidylate synthase in binary complex with a substrate analogue and strong inhibitor, N(4)-hydroxy-2'-deoxycytidine-5'-monophosphate== | |
| - | + | <StructureSection load='4ein' size='340' side='right' caption='[[4ein]], [[Resolution|resolution]] 1.75Å' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4ein]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EIN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EIN FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NOH:2-DEOXY-N-HYDROXYCYTIDINE+5-(DIHYDROGEN+PHOSPHATE)'>NOH</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Tyms ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ein FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ein OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ein RCSB], [http://www.ebi.ac.uk/pdbsum/4ein PDBsum]</span></td></tr> | ||
| + | </table> | ||
| - | == | + | ==See Also== |
| - | [[ | + | *[[Thymidylate synthase|Thymidylate synthase]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Thymidylate synthase]] | [[Category: Thymidylate synthase]] | ||
| - | [[Category: Dowiercial, A | + | [[Category: Dowiercial, A]] |
| - | [[Category: Jarmula, A | + | [[Category: Jarmula, A]] |
| - | [[Category: Kierdaszuk, B | + | [[Category: Kierdaszuk, B]] |
| - | [[Category: Rode, W | + | [[Category: Rode, W]] |
| - | [[Category: Rypniewski, W R | + | [[Category: Rypniewski, W R]] |
| - | [[Category: Wilk, P | + | [[Category: Wilk, P]] |
[[Category: Binding site]] | [[Category: Binding site]] | ||
[[Category: Catalysis]] | [[Category: Catalysis]] | ||
Revision as of 10:54, 21 December 2014
Crystal structure of mouse thymidylate synthase in binary complex with a substrate analogue and strong inhibitor, N(4)-hydroxy-2'-deoxycytidine-5'-monophosphate
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