4fqs
From Proteopedia
(Difference between revisions)
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| - | + | ==Crystal Structure of Mycobacterium tuberculosis ThyA in complex with UMP and Pemetrexed== | |
| - | + | <StructureSection load='4fqs' size='340' side='right' caption='[[4fqs]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4fqs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_h37rv Mycobacterium tuberculosis h37rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FQS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FQS FirstGlance]. <br> | ||
| + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LYA:2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-PENTANEDIOIC+ACID'>LYA</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr> | ||
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3qj7|3qj7]], [[4fox|4fox]], [[4fog|4fog]], [[4foa|4foa]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MT2834, MTV002.29c, Rv2764c, thyA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 Mycobacterium tuberculosis H37Rv])</td></tr> | ||
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fqs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fqs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4fqs RCSB], [http://www.ebi.ac.uk/pdbsum/4fqs PDBsum]</span></td></tr> | ||
| + | </table> | ||
| - | == | + | ==See Also== |
| - | [[ | + | *[[Thymidylate synthase|Thymidylate synthase]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
[[Category: Mycobacterium tuberculosis h37rv]] | [[Category: Mycobacterium tuberculosis h37rv]] | ||
[[Category: Thymidylate synthase]] | [[Category: Thymidylate synthase]] | ||
| - | [[Category: Bruning, J B | + | [[Category: Bruning, J B]] |
| - | [[Category: Harshbarger, W | + | [[Category: Harshbarger, W]] |
| - | [[Category: Reddy, M C.M | + | [[Category: Reddy, M C.M]] |
| - | [[Category: Sacchettini, J C | + | [[Category: Sacchettini, J C]] |
[[Category: Folate binding]] | [[Category: Folate binding]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Transferase-transferase inhibitor complex]] | [[Category: Transferase-transferase inhibitor complex]] | ||
Revision as of 11:30, 21 December 2014
Crystal Structure of Mycobacterium tuberculosis ThyA in complex with UMP and Pemetrexed
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