4dt0
From Proteopedia
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| - | + | ==The structure of the peripheral stalk subunit E from Pyrococcus horikoshii== | |
| - | + | <StructureSection load='4dt0' size='340' side='right' caption='[[4dt0]], [[Resolution|resolution]] 3.65Å' scene=''> | |
| - | + | == Structural highlights == | |
| + | <table><tr><td colspan='2'>[[4dt0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii_ot3 Pyrococcus horikoshii ot3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DT0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4DT0 FirstGlance]. <br> | ||
| + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2dm9|2dm9]], [[2dma|2dma]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">atpE, PH1978 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=70601 Pyrococcus horikoshii OT3])</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dt0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dt0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4dt0 RCSB], [http://www.ebi.ac.uk/pdbsum/4dt0 PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | A(1)A(O) ATP synthases are the major energy converters of archaea. They are composed of an A(1) region that synthesizes ATP and an integral part A(O) that conducts ions. Subunit E is a component of the peripheral stalk that links the A(1) with the A(O) part of the A-ATP synthase. We have determined the crystal structure of the entire subunit E (PhE) of the Pyrococcus horikoshii OT3 A-ATP synthase at 3.6 A resolution. The structure reveals an extended S-shaped N-terminal alpha-helix with 112.29 A in length, followed by a globular head group. The S-shaped feature, common in elastic connectors and spacers, would facilitate the storage of transient elastic energy during rotary motion in the enzyme. The structure has been superimposed into the asymmetric peripheral stalks of the three-dimensional reconstruction of the Pyrococcus furiosus enzyme, revealing that the S-shaped subunit PhE fits well into the bent peripheral stalk, whereas the previously solved E subunit structure (3.1 A resolution) of Thermus thermophilus A-ATP synthase is well accommodated in the density of the straight stator domain. The different features of the two stalk subunits are discussed in light of a novel coupling mechanism in A-ATP synthases proposed to differ from the Wankel engine of F-ATP synthases. | ||
| - | + | The Structure of Subunit E of the Pyrococcus horikoshii OT3 A-ATP Synthase Gives Insight into the Elasticity of the Peripheral Stalk.,Balakrishna AM, Hunke C, Gruber G J Mol Biol. 2012 Apr 16. PMID:22516614<ref>PMID:22516614</ref> | |
| - | + | ||
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
==See Also== | ==See Also== | ||
| - | *[[ | + | *[[ATPase|ATPase]] |
| - | + | == References == | |
| - | == | + | <references/> |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
[[Category: Pyrococcus horikoshii ot3]] | [[Category: Pyrococcus horikoshii ot3]] | ||
| - | [[Category: Balakrishna, A M | + | [[Category: Balakrishna, A M]] |
| - | [[Category: Gruber, G | + | [[Category: Gruber, G]] |
[[Category: A-atp synthase]] | [[Category: A-atp synthase]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Peripheral stalk]] | [[Category: Peripheral stalk]] | ||
Revision as of 11:34, 21 December 2014
The structure of the peripheral stalk subunit E from Pyrococcus horikoshii
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