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4h0u

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{{STRUCTURE_4h0u| PDB=4h0u | SCENE= }}
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==Crystal structure of thymidylate synthase from Corynebacterium glutamicum in complex with dUMP==
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===Crystal structure of thymidylate synthase from Corynebacterium glutamicum in complex with dUMP===
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<StructureSection load='4h0u' size='340' side='right' caption='[[4h0u]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4h0u]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Corynebacterium_glutamicum_atcc_13032 Corynebacterium glutamicum atcc 13032]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H0U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4H0U FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cg0966, Cgl0844, thyA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=196627 Corynebacterium glutamicum ATCC 13032])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h0u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4h0u RCSB], [http://www.ebi.ac.uk/pdbsum/4h0u PDBsum]</span></td></tr>
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</table>
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==Function==
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==See Also==
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[[http://www.uniprot.org/uniprot/TYSY_CORGL TYSY_CORGL]] Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity).
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*[[Thymidylate synthase|Thymidylate synthase]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[4h0u]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Corynebacterium_glutamicum_atcc_13032 Corynebacterium glutamicum atcc 13032]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H0U OCA].
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[[Category: Corynebacterium glutamicum atcc 13032]]
[[Category: Corynebacterium glutamicum atcc 13032]]
[[Category: Thymidylate synthase]]
[[Category: Thymidylate synthase]]
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[[Category: Chang, C M.]]
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[[Category: Chang, C M]]
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[[Category: Wang, W C.]]
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[[Category: Wang, W C]]
[[Category: Dump]]
[[Category: Dump]]
[[Category: Nucleotide]]
[[Category: Nucleotide]]
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 11:36, 21 December 2014

Crystal structure of thymidylate synthase from Corynebacterium glutamicum in complex with dUMP

4h0u, resolution 2.75Å

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