4el6
From Proteopedia
(Difference between revisions)
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| - | + | ==Crystal structure of IPSE/alpha-1 from Schistosoma mansoni eggs== | |
| - | + | <StructureSection load='4el6' size='340' side='right' caption='[[4el6]], [[Resolution|resolution]] 1.71Å' scene=''> | |
| - | + | == Structural highlights == | |
| + | <table><tr><td colspan='2'>[[4el6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EL6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EL6 FirstGlance]. <br> | ||
| + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4el6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4el6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4el6 RCSB], [http://www.ebi.ac.uk/pdbsum/4el6 PDBsum]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The interleukin-4-inducing principle from Schistosoma mansoni eggs (IPSE/alpha-1) triggers the release of large amounts of interleukin-4 from human blood basophils, thus presumably playing an immunomodulatory role during schistosome infection. IPSE/alpha-1 was crystallized and a native X-ray data set was collected to 1.66 A resolution from a single crystal at 100 K using synchrotron radiation. The crystal belonged to space group P6(1) or P6(5), with one molecule per asymmetric unit. | ||
| - | + | Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of interleukin-4-inducing principle from Schistosoma mansoni eggs (IPSE/alpha-1).,Mayerhofer H, Schramm G, Hatzopoulos GN, Mueller-Dieckmann C, Haas H, Mueller-Dieckmann J Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Jun 1;65(Pt 6):594-6. doi:, 10.1107/S1744309109015899. Epub 2009 May 22. PMID:19478439<ref>PMID:19478439</ref> | |
| - | + | ||
| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Schistosoma mansoni]] | [[Category: Schistosoma mansoni]] | ||
| - | [[Category: Bade, S | + | [[Category: Bade, S]] |
| - | [[Category: Barths, D | + | [[Category: Barths, D]] |
| - | [[Category: Blindow, S | + | [[Category: Blindow, S]] |
| - | [[Category: Frey, A | + | [[Category: Frey, A]] |
| - | [[Category: Haas, H | + | [[Category: Haas, H]] |
| - | [[Category: Madl, T | + | [[Category: Madl, T]] |
| - | [[Category: Mayerhofer, H | + | [[Category: Mayerhofer, H]] |
| - | [[Category: Meyer, H | + | [[Category: Meyer, H]] |
| - | [[Category: Mueller-Dieckmann, J | + | [[Category: Mueller-Dieckmann, J]] |
| - | [[Category: Sattler, M | + | [[Category: Sattler, M]] |
| - | [[Category: Schramm, G | + | [[Category: Schramm, G]] |
| - | [[Category: Tripsianes, K | + | [[Category: Tripsianes, K]] |
[[Category: Beta/gamma-crystallin superfamily]] | [[Category: Beta/gamma-crystallin superfamily]] | ||
[[Category: Ige]] | [[Category: Ige]] | ||
[[Category: Signaling protein]] | [[Category: Signaling protein]] | ||
[[Category: Triggers il4 release]] | [[Category: Triggers il4 release]] | ||
Revision as of 11:37, 21 December 2014
Crystal structure of IPSE/alpha-1 from Schistosoma mansoni eggs
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