4hlj

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{{STRUCTURE_4hlj| PDB=4hlj | SCENE= }}
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==Axon Guidance Receptor==
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===Axon Guidance Receptor===
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<StructureSection load='4hlj' size='340' side='right' caption='[[4hlj]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[4hlj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HLJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HLJ FirstGlance]. <br>
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[[http://www.uniprot.org/uniprot/ROBO1_HUMAN ROBO1_HUMAN]] Receptor for SLIT1 and SLIT2 which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex. May be required for lung development.<ref>PMID:10102268</ref>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DUTT1, ROBO1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hlj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hlj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hlj RCSB], [http://www.ebi.ac.uk/pdbsum/4hlj PDBsum]</span></td></tr>
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[[4hlj]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HLJ OCA].
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</table>
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__TOC__
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==Reference==
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</StructureSection>
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<references group="xtra"/><references/>
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[[Category: Human]]
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[[Category: Barak, R.]]
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[[Category: Barak, R]]
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[[Category: Opatowsky, Y.]]
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[[Category: Opatowsky, Y]]
[[Category: Cell adhesion]]
[[Category: Cell adhesion]]

Revision as of 12:32, 21 December 2014

Axon Guidance Receptor

4hlj, resolution 1.80Å

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