4is3

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{{STRUCTURE_4is3| PDB=4is3 | SCENE= }}
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==Crystal structure of a 3alpha-hydroxysteroid dehydrogenase (BaiA2) associated with secondary bile acid synthesis from Clostridium scindens VPI12708 in complex with a putative NAD(+)-OH- adduct at 2.0 A resolution==
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===Crystal structure of a 3alpha-hydroxysteroid dehydrogenase (BaiA2) associated with secondary bile acid synthesis from Clostridium scindens VPI12708 in complex with a putative NAD(+)-OH- adduct at 2.0 A resolution===
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<StructureSection load='4is3' size='340' side='right' caption='[[4is3]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4is3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_scindens Clostridium scindens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IS3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IS3 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4is2|4is2]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">baiA, BAIA2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=29347 Clostridium scindens])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4is3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4is3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4is3 RCSB], [http://www.ebi.ac.uk/pdbsum/4is3 PDBsum]</span></td></tr>
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</table>
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==Function==
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==See Also==
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[[http://www.uniprot.org/uniprot/BAIA2_EUBSP BAIA2_EUBSP]] 7-alpha-dehydroxylation of cholic acid and chenodeoxycholate, yielding deoxycholic acid and lithocholic acid, respectively. Highest affinity with taurochenodeoxycholic acid.
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*[[Hydroxysteroid dehydrogenase|Hydroxysteroid dehydrogenase]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[4is3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_scindens Clostridium scindens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IS3 OCA].
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[[Category: Clostridium scindens]]
[[Category: Clostridium scindens]]
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[[Category: JCSG, Joint Center for Structural Genomics.]]
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[[Category: Structural genomic]]
[[Category: Jcsg]]
[[Category: Jcsg]]
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[[Category: Joint center for structural genomic]]
 
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
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[[Category: Protein structure initiative]]
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[[Category: PSI, Protein structure initiative]]
[[Category: Psi-biology]]
[[Category: Psi-biology]]
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[[Category: Structural genomic]]
 

Revision as of 12:42, 21 December 2014

Crystal structure of a 3alpha-hydroxysteroid dehydrogenase (BaiA2) associated with secondary bile acid synthesis from Clostridium scindens VPI12708 in complex with a putative NAD(+)-OH- adduct at 2.0 A resolution

4is3, resolution 2.00Å

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