4jek

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{{STRUCTURE_4jek| PDB=4jek | SCENE= }}
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==Structure of dibenzothiophene monooxygenase (DszC) from Rhodococcus erythropolis==
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===Structure of dibenzothiophene monooxygenase (DszC) from Rhodococcus erythropolis===
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<StructureSection load='4jek' size='340' side='right' caption='[[4jek]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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{{ABSTRACT_PUBMED_23722833}}
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4jek]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_sp._igts8 Rhodococcus sp. igts8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JEK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4JEK FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">soxC, dszC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=54064 Rhodococcus sp. IGTS8])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jek FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jek OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4jek RCSB], [http://www.ebi.ac.uk/pdbsum/4jek PDBsum]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Dibenzothiophene (DBT) and its derivatives are typical sulfur compounds found in fossil fuels. These compounds show resistance to the hydrodesulfurization treatment that is commonly used in industry. Dibenzothiophene monooxygenase (DszC) is responsible for the oxidation of DBT, which is the first and the rate-limiting step in the DBT enzymatic desulfurization 4S pathway. In this study, the crystal structure of DszC from Rhodococcus erythropolis DS-3 is reported. The crystal of native DszC belonged to space group P1, with unit-cell parameters a = 96.16, b = 96.27, c = 98.56 A, alpha = 81.03, beta = 67.57, gamma = 85.84 degrees . To determine the phase, SAD X-ray diffraction data were collected from a SeMet-derivative DszC crystal, which also belonged to space group P1, with unit-cell parameters a = 95.379, b = 95.167, c = 94.891 A, alpha = 87.046, beta = 70.536, gamma = 79.738 degrees . Further structural analysis of DszC is in progress.
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==Function==
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Crystallization and preliminary structural analysis of dibenzothiophene monooxygenase (DszC) from Rhodococcus erythropolis.,Duan X, Zhang L, Zhou D, Ji K, Ma T, Shui W, Li G, Li X Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Jun;69(Pt 6):597-601. doi:, 10.1107/S1744309113011172. Epub 2013 May 23. PMID:23722833<ref>PMID:23722833</ref>
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[[http://www.uniprot.org/uniprot/SOXC_RHOSG SOXC_RHOSG]] Part of a pathway to remove covalently bound sulfur from dibenzothiophene (DBT) without breaking carbon-carbon bonds. Sulfur dioxygenase which converts DBT to DBT-sulfone (DBTO2 or DBT 5,5-dioxide).
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==About this Structure==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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[[4jek]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_sp._igts8 Rhodococcus sp. igts8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JEK OCA].
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</div>
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:023722833</ref><references group="xtra"/><references/>
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__TOC__
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</StructureSection>
[[Category: Rhodococcus sp. igts8]]
[[Category: Rhodococcus sp. igts8]]
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[[Category: Duan, X L.]]
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[[Category: Duan, X L]]
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[[Category: Li, X.]]
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[[Category: Li, X]]
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[[Category: Zhang, L.]]
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[[Category: Zhang, L]]
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[[Category: Zhou, D M.]]
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[[Category: Zhou, D M]]
[[Category: Dibenzothiophene desulfurization enzyme c]]
[[Category: Dibenzothiophene desulfurization enzyme c]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]

Revision as of 12:48, 21 December 2014

Structure of dibenzothiophene monooxygenase (DszC) from Rhodococcus erythropolis

4jek, resolution 2.40Å

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